Assessment of hyaluronic acid in COPD patients as a prognostic biomarker

The Egyptian Journal of Bronchology

Table 6 ROC curve for the performance of HA in predicting FEV1 during the three visits

	AUC	Cutoff value	Sensitivity	Specificity	p-value	95% confidence interval
	AUC	Cutoff value	Sensitivity	Specificity	p-value	Lower bound	Upper bound
1st visit	0.823	≥ 275	73.7%	81%	0.000^**	0.719	0.926
2nd visit	0.663	≥ 215	72.4%	53.3%	0.03^*	0.524	0.802
3rd visit	0.753	≥ 165	82.8%	56.7%	0.001^*	0.628	0.877

ROC receiver operating characteristic, FEV1 forced expiratory volume in the first second, AUC area under the curve
^*Significant
^**Strong significant