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Table 2 The allele frequency of the genotypes of MUC5B promoter polymorphism among the 3 studied groups

From: A preliminary study: MUC5B promoter polymorphism and its association with IPF

 

IPF patients (group I) (n = 42)

Other ILD patients (group II) (n = 47)

Control subjects (group III) (n = 40)

P value

Pairs

Genotype

     

TT

5 (11.9%)

2 (4.3%)

2 (5%)

0.003

1*2 = 0.043

GT

21 (50%)

15 (31.9%)

6 (15%)

 

1*3 = 0.001

GG

16 (38.1%)

30 (63.8%)

32 (80%)

 

2*3 = 0.184

Genotype

    

1*2 = 0.015

TT or GT

26 (61.9%)

17 (36.2%)

8 (20%)

< 0.001

1*3 < 0.001

GG

16 (38.1%)

30 (63.8%)

32 (80%)

 

2*3 = 0.097