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Table 4 Correlation between some biomarkers and dyspnea score in UIP group before treatment

From: Non-invasive IGFBP1, IGFBP2 biomarkers as predictors and outcomes of usual interstitial pneumonia (UIP) therapeutic response

 

IGFBP1 in serum

IGFBP2 in serum

IGFBP1 in BAL

IGFBP2 in BAL

6MWT

SPaO2

Dyspnea score

IGFBP1 in serum

1

      

IGFBP2 in serum

0.154

1

     

IGFBP1 in BAL

− 0.052

0.371

1

    

IGFBP2 in BAL

− 0.194

0.615**

0.143

1

   

6MWT

− 0.036

− 0.166

0.435*

− 0.008

1

  

SPaO2

0.033

0.051

− 0.007

0.130

− 0.094

1

 

Dyspnea score

0.278

0.257

0.256

0.085

− 0.171

0.036

1

  1. IGFBP1 insulin-like growth factor binding protein 1, IGFBP2 insulin-like growth factor binding protein 2, BAL bronchoalveolar lavage, 6MWT 6 min walking test, SPaO2 O2 saturation
  2. *Correlation is significant at the 0.05 level (2-tailed)
  3. **Correlation is significant at the 0.01 level