Table 2 Comparison of the clinical presentation outcomes, respiratory function tests, arterial blood gases, and the mean Karnofsky performance score for group A (EBCT+CRT) and group B (CRT) at baseline and follow-up after the procedure
Variable | Group A | Group B | P values I & II | P values I & III | P values II & IV | P values III & IV | |||
|---|---|---|---|---|---|---|---|---|---|
Pre-cryotherapy (I) (n=30) | Post-cryotherapy (II) (n=30) | Pre-therapy (III) (n=30) | Post therapy (IV) (n=30) | ||||||
Clinical presentation | Cough | 24 (80%) | 6(20%) | 24 (80%) | 22(73%) | <0.001 | 1.000 | <0.001 | 0.592 |
Dyspnea | 26 (87%) | 6(20%) | 28 (93%) | 24(80%) | <0.001 | 0.667 | <0.001 | 0.254 | |
Hemoptysis | 30 (100%) | 0 | 28 (93%) | 26(87%) | <0.001 | 0.472 | <0.001 | 0.667 | |
Chest pain | 12 (40%) | 6(20%) | 10 (32%) | 8(27%) | 0.090 | 0.592 | 0.541 | 0.573 | |
Respiratory function tests | Mean FVC % | 62.13±2.8 | 65±3.65 | 62.47±1.8 | 62.53±1.7 | 0.001 | 0.578 | 0.001 | 0.895 |
Mean FEV1 % | 64.53±3.8 | 69.87±4.0 | 65±2.9 | 65±2.6 | <0.001 | 0.592 | <0.001 | 1.000 | |
Mean 6MWT (m) | 262±56 | 330±76 | 287±78 | 292±48 | <0.001 | 0.159 | 0.024 | 0.766 | |
Arterial blood gases | Mean PH | 7.382±.02 | 7.385±.01 | 7.381±.01 | 7.39±0.03 | 0.465 | 0.807 | 0.390 | 0.124 |
Mean So2 | 87.07±1.8 | 90.4±1.5 | 86.7±1.9 | 87±1.7 | <0.001 | 0.442 | <0.001 | 0.522 | |
Mean PaO2 | 77.07±1.8 | 82.9±1.8 | 76.9±2.4 | 77.3±2.6 | <0.001 | 0.757 | <0.001 | 0.538 | |
Mean PaCo2 | 36.9±1.6 | 41±1.1 | 37.7±1.8 | 38.2±1.9 | <0.001 | 0.074 | <0.001 | 0.300 | |
Mean Karnofsky performance score % | 57.33±5.67 | 60.67±6.39 | 56.87±9.19 | 56.32±9.63 | 0.036 | 0.816 | 0.044 | 0.822 | |