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Table 2 Comparison of the clinical presentation outcomes, respiratory function tests, arterial blood gases, and the mean Karnofsky performance score for group A (EBCT+CRT) and group B (CRT) at baseline and follow-up after the procedure

From: The value of endobronchial cryotherapy in the management of malignant endobronchial obstruction in patients with inoperable NSCLC: a prospective analysis of clinical and survival outcomes

Variable Group A Group B P values I & II P values
I & III
P values II & IV P values III & IV
Pre-cryotherapy
(I)
(n=30)
Post-cryotherapy
(II)
(n=30)
Pre-therapy
(III)
(n=30)
Post therapy
(IV)
(n=30)
Clinical presentation Cough 24 (80%) 6(20%) 24 (80%) 22(73%) <0.001 1.000 <0.001 0.592
Dyspnea 26 (87%) 6(20%) 28 (93%) 24(80%) <0.001 0.667 <0.001 0.254
Hemoptysis 30 (100%) 0 28 (93%) 26(87%) <0.001 0.472 <0.001 0.667
Chest pain 12 (40%) 6(20%) 10 (32%) 8(27%) 0.090 0.592 0.541 0.573
Respiratory function tests Mean FVC % 62.13±2.8 65±3.65 62.47±1.8 62.53±1.7 0.001 0.578 0.001 0.895
Mean FEV1 % 64.53±3.8 69.87±4.0 65±2.9 65±2.6 <0.001 0.592 <0.001 1.000
Mean 6MWT (m) 262±56 330±76 287±78 292±48 <0.001 0.159 0.024 0.766
Arterial blood gases Mean PH 7.382±.02 7.385±.01 7.381±.01 7.39±0.03 0.465 0.807 0.390 0.124
Mean So2 87.07±1.8 90.4±1.5 86.7±1.9 87±1.7 <0.001 0.442 <0.001 0.522
Mean PaO2 77.07±1.8 82.9±1.8 76.9±2.4 77.3±2.6 <0.001 0.757 <0.001 0.538
Mean PaCo2 36.9±1.6 41±1.1 37.7±1.8 38.2±1.9 <0.001 0.074 <0.001 0.300
Mean Karnofsky performance score % 57.33±5.67 60.67±6.39 56.87±9.19 56.32±9.63 0.036 0.816 0.044 0.822