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Table 2 Laboratory data of COVID-19 patients included in the study (n = 351)

From: Prognostic biomarkers in COVID-19 infection: value of anemia, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and D-dimer

  Non-ICU patients
(n = 206)
Admitted to ICU
(n = 145)
p value*
CBC
Hemoglobin (g/dl) 12.7 ± 1.7 11.8 ± 2.0 < 0.001 ^
  Anemic (HB < 12) 59 (28.6%) 82 (56.6%) < 0.001 ^
WBCs (103/ul) 7.9 ± 4.5 10.6 ± 6.1 < 0.001 ^
  Low (< 4) 31 (15.1%) 11 (7.6%) < 0.001 ^
  High (> 10) 49 (23.8%) 72 (49.7%)
Neutrophil (103/ul) 5.7 ± 4.5 8.7 ± 5.5 < 0.001 ^
  High (> 7) 67 (32.5%) 92 (63.4%) < 0.001 ^
Lymphocytes (%) 24.7 ± 14.3 13.0 ± 12.7 < 0.001 ^
  Low (< 20) 99 (48.1%) 115 (79.3%) < 0.001 ^
Lymphocytes (103/ul) 1.6 ± 0.9 1.0 ± 0.8 < 0.001 ^
  Low (< 1.5) 119 (57.8%) 116 (80%) < 0.001 ^
Platelets (103/ul) 273.3 ± 131.5 279.5 ± 137.4 0.672
  High (> 450) 20 (9.7%) 14 (9.7%) 0.987
NLR 4.7 ± 5.0 15.5 ± 23.2 < 0.001 ^
  High (> 8) 29 (14.1%) 89 (61.4%) < 0.001 ^
PLR 231.8 ± 207.4 417.2 ± 342.7 < 0.001 ^
  High (> 192) 83 (40.3%) 108 (74.5%) < 0.001 ^
INR 1.04 ± 0.12 1.13 ± 0.24 < 0.001 ^
  High (≥ 1.1) 31 (15%) 51 (35.2%) < 0.001 ^
Liver function tests
Albumin (g/L) 33.6 ± 6.2 30.6 ± 6.9 < 0.001 ^
  Low (< 34) 118 (57.3%) 99 (68.3%) 0.037
Total bilirubin (umol/L) 7.6 ± 6.5 11.7 ± 11.5 < 0.001 ^
  High (> 21) 7 (3.4%) 10 (6.9%) 0.133
AST (U/L) 42.8 ± 69.5 67.1 ± 101.9 < 0.001 ^
  High (> 34) 90 (43.7%) 85 (58.6%) 0.006
ALT (U/L) 43.8 ± 65.3 73.7 ± 149.7 0.001 ^
  High (> 45) 58 (28.2%) 67 (46.2%) 0.001 ^
Kidney function tests
Serum creatinine (umol/L) 100.0 ± 70.8 141.3 ± 142.9 0.022 ^
  High (> 97) 82 (39.8%) 68 (46.9%) 0.186
BUN (mmol/L) 13.8 ± 15.8 18.7 ± 19.2 < 0.001 ^
  High (> 8.2) 90 (43.7%) 105 (72.4%) < 0.001 ^
Ferritin (ng/ml) 491.4 ± 608.9 1161.5 ± 1321.1 < 0.001 ^
  High (> 440) 69 (33.5%) 103 (71%) < 0.001 ^
D-dimer (mg/L) 1.3 ± 2.3 4.0 ± 6.8 < 0.001 ^
  High (> 0.9) 66 (32%) 106 (73.1%) < 0.001 ^
CRP (mg/dl) 37.9 ± 49.5 80.7 ± 76.1 < 0.001 ^
  High (> 23) 97 (47.1%) 111 (76.6%) < 0.001 ^
  1. CBC complete blood picture, WBCs white blood cells, NLR neutrophil lymphocytic ratio, PLR platelets lymphocytic ratio, INR international normalization ratio, AST aspartate aminotransferase, ALT alanine aminotransferase, BUN blood urea nitrogen, CRP C-reactive protein
  2. *Mann-Whitney and chi-square test were used.
  3. ^Significant p value