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Table 2 Recorded adverse effects of ChAdOx1 nCoV-19 vaccine

From: To what extent AstraZeneca ChAdOx1 nCoV-19 vaccine is safe and effective? Rapid systematic review

 

PR

95% CI

P value

Chi square p value

I2

Frequency

Female

0.683

0.569–0.797

< 0.001

< 0.001

99.983

427,613/635,109

Number of cases showing more than one adverse events

0.717

0.339–1.094

< 0.001

< 0.001

99.99

123,969/353,302

Yougner people with at least one adverse event

0.579

0.143–1.014

0.009

< 0.001

99.998

36,191/171,241

Older people with at least one adverse event

0.439

0.245–0.633

< 0.001

< 0.001

99.997

86,811/381,653

Systemic side effects

 Malaise

0.717

0.479–0.955

< 0.001

< 0.001

99.019

1156/1537

 Fatigue

0.622

0.263–0.982

< 0.001

< 0.001

99.978

79,230/353,837

 Headache

0.569

0.288–0.850

< 0.001

< 0.001

99.951

84,436/353,837

 Muscle pain

0.516

0.035–0.998

0.036

< 0.001

99.985

29,927/352,843

 Chills

0.483

0.189–0.778

0.001

< 0.001

99.952

55,985/353,837

 Joint pain

0.357

0.142–0.572

0.001

< 0.001

99.908

43,522/353,837

 Fever

0.346

0.109–0.582

0.004

< 0.001

99.922

32149/353837

 Nausea

0.228

0.072–0.383

0.004

< 0.001

99.608

20,341/348,248

 Vomiting

0.209

0.044–0.374

0.013

< 0.001

99.774

1688/8014

 Diarrhea

0.154

− 0.016–0.324

0.077

< 0.001

99.879

9091/351,863

 Bleeding

0.149

− 0.211–0.508

0.418

0.029

79.137

77/281,272

Local side effects

 Local pain

0.645

0.203–1.087

0.004

< 0.001

99.986

40,820/353,837

 Itching

0.415

− 0.349–1.178

0.287

< 0.001

100

8736/351,412

 Swelling

0.161

0.078–0.244

< 0.001

< 0.001

99.73

10,823/352,406

 Redness

0.14

0.080–0.199

< 0.001

< 0.001

99.61

8538/353,837

 Skin rash

0.031

− 0.021–0.083

0.249

< 0.001

99.65

1752/350,869

 Death

0.148

− 0.211–0.508

0.418

0.028

79.161

18/281,272

Thrombosis events

 Percentage of thrombosis to total number of vaccinated Population

0

− 0.000–0.000

0.371

0.033

78.123

33/17,132,686

 Number of cases showing more than one thrombosis events

0.515

0.281–0.749

< 0.001

< 0.001

84.009

31/83

 Deep venous thrombosis

0.164

− 0.005–0.333

0.057

< 0.001

92.401

77/281,323

 Thrombosis in other organs/areas

0.323

0.108–0.538

0.003

< 0.001

93.471

57/281344

 Cerebral venous sinus thrombosis

0.525

0.309–0.742

< 0.001

< 0.001

96.415

46/281,347

 Pulmonary embolism

0.191

0.028–0.353

0.021

< 0.001

83.733

38/281,334

 Splanchnic vein thrombosis

0.103

− 0.156–0.363

0.435

0.042

75.745

23/281,275

 Death

0.132

0.008–0.257

0.037

< 0.001

79.289

29/281,334