Criteria and potential predictors of severity in patients with COVID-19

The Egyptian Journal of Bronchology

Table 4 Laboratory assessment of the studied COVID-19 patients on admission

Variables	Mild/moderate (n = 169)	Severe/critical (n = 33)	P-value
Laboratory investigation
TLC	5.97 ± 1.92	6.7 ± 3.4	0.19*
Platelet	201.3 ± 61.9	187.5 ± 70.2	0.23*
HgB	15.3 ± 1.6	14.2 ± 2.6	0.02*
%Lymph	42.1 ± 7.8	16.2 ± 7.1	< 0.001*
MPV	10.5 ± 1.8	12.8 ± 7.1	< 0.001*
ESR	39 ± 19.6	60.4 ± 17.7	< 0.001*
CRP	59.6 ± 39.5	119.5 ± 45.6	< 0.001*
Ferritin	447 ± 166	954 ± 138	< 0.001*
Positive D-dimer	35 (20.7%)	25 (75.8%)	< 0.001^‡
LDH	384 ± 183	604 ± 220	< 0.001*
AST	51.7 ± 25.4	69 ± 37	0.01*
ALT	48.2 ± 26.5	59. 5 ± 17.7	0.01*
Creatinine	0.8 ± 0.2	1.3 ± 0.7	0.01*
CPK-MB	16.4 ± 4.9	24.3 ± 5.8	< 0.001*
ABG
PH	7.4 ± 0.3	7.4 ± 0.6	0.06
PCO₂	37.4 ± 3.6	32 ± 3.9	< 0.001*
PO₂	70.8 ± 9.3	49.6 ± 2.6	< 0.001*
HCO₃	20.9 ± 1.97	19.6 ± 2.8	0.03*
Na	131.7 ± 4.5	129.7 ± 4.7	0.03*
K	3.5 ± 0.4	3.2 ± 0.6	0.02*

Continuous data represented as mean and SD, and categorical data represented as number and percentage (%).*Independent samples Student’s t-test; ^‡chi-square test; P < 0.05 is significant; TLC, total leucocyte count (cell/μL)³; PLT, platelet count (cell/μL)³; HgB, hemoglobin (gm/dL); %Lymph (cell/μL)³; MPV, mean platelet volume (fL); ESR, erythrocyte sedimentation rate (mm/h); CRP, C-reactive protein (mg/L); ferritin (ng/ml); D-dimer, (mg/L); LDH, lactate dehydrogenase (U/L); AST, aspartate transaminase (U/L); ALT, alanine aminotransferase (U/L); creatinine (mg/dL); CPK-MB, creatine kinase myocardial band (IU/L); PCO₂, partial pressure of arterial carbon dioxide (mm HG); PO₂, partial pressure of arterial oxygen (mm HG); Na, sodium (mEq/L); K, potassium (mmol/L)