Table 1 Descriptive characteristics of the studied groups
From: Serum interleukin 38 (IL-38) as a new potential biomarker of pediatric asthma
HC (n=30) | Asthmatic patients (n=73) | p-valuea | Atopic patients (n=34) | Non-atopic patients (n=39) | p-valueb | |
|---|---|---|---|---|---|---|
Age, years | 8.6 ± 2.9 | 8.4 ± 2.5 | 0.739 | 8.7 ± 2.2 | 8.1 ± 2.7 | 0.311 |
Male sex, n (%) | 11 (36.7) | 40 (54.8) | 0.095 | 18 (52.9) | 22 (56.4) | 0.766 |
Laboratory | ||||||
Total IgE, (IU/mL) | 7.7 (5.4–20.9) | 31.6 (14.3–209.8) | <0.001 | 62.5 (17.9–292.3) | 27.6 (9.1–165.4) | 0.034 |
Eosinophils % in PB | 4.0 (2.0–7.0) | 4.0 (2.0–7.0) | 4.0 (2.0–7.0) | 0.327 | ||
Absolute eosinophils count (cells/ul) | 294 (135–522) | 334 (144–566) | 255 (122–485) | 0.197 | ||
Exacerbation, n (%) | ||||||
Seasonal | 50 (68.5) | 24 (70.6) | 26 (66.7) | 0.719 | ||
Perennial | 23 (31.5) | 10 (29.4) | 13 (33.3) | |||
Pulmonary functions | ||||||
FEV1 | 86.4 ± 17.2 | 87.7 ± 13.7 | 85.3 ± 19.8 | 0.609 | ||
FVC | 86.8 ± 15.4 | 89.3 ± 11.0 | 84.8 ± 18.3 | 0.277 | ||
FEV1/FVC | 98.5 ± 11.1 | 96.2 ± 11.0 | 100.5 ± 11.0 | 0.139 | ||
ACT | 18.6 ± 4.6 | 17.7 ± 5.1 | 19.4 ± 4.1 | 0.121 | ||
Asthma control, n (%) | ||||||
Poor | 41 (56.2) | 23 (67.6) | 18 (46.2) | 0.065 | ||
Good | 32 (43.8) | 11 (32.4) | 21 (53.8) | |||
Eosinophilic asthma, n (%) | 50 (68.5) | 24 (70.6) | 26 (66.7) | 0.719 | ||