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Table 1 Cough severity in patients with post-COVID-19 cough measured by number of paroxysms, visual analogue scale (VAS), cough severity index, and cough quality-of-life questionnaire after 14-day treatment with montelukast 10 mg (n = 68 patients)

From: Value of montelukast as a potential treatment of post-COVID-19 persistent cough: a non-randomized controlled pilot study

 

Cough severity in day 1 in study groups (n = 68)

Cough severity after 14-day montelukast therapy* (n = 32)

Cough severity in controls after 14 days standard therapy# (n = 36)

p-value

Number of paroxysms/days

12 ± 3.1

3 ± 1.2*

10 ± 4.1#

*#< 0.01

Cough severity VAS

76 ± 19

12 ± 6*

66 ± 12#

< 0.001

Cough severity index

21 ± 2

4 ± 1.1*

20 ± 5#

< 0.01

Cough quality of life questionnaire

87 ± 4.9

18 ± 2.5*

98 ± 2#

< 0.01

Days needed for improvement

-

5 ± 1.4

10 ± 1.5#

#< 0.05

Side effectsa

-

6 (18.7)

-

N/A

  1. Data were expressed as number (%), mean ± SD. VAS visual analogue scale (100 mm); cough VAS: 0 = no cough, 100 = worst cough ever. *Variance before and after montelukast, #variance between intervention group and controls.
  2. aUpper respiratory contagion (infection in the nose or throat), fever, headache, sore throat, cough, stomach pain, diarrhea, earache, or ear infection