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Table 5 Relation between kidney injury and APACHE II score, MV parameters, duration of ICU stay, and GFR among the studied groups

From: Effect of acute kidney injury on weaning from mechanical ventilation in chronic obstructive pulmonary diseases patients with respiratory failure

Variable Non-AKI (no. = 42)
Mean ± SD
AKI (no. = 58)
Mean ± SD
Test P
APACHE II score 17.19 ± 4.79 21.65 ± 6.77 Z = 2 0.04
Mechanical ventilation parameters PEEP 5 ± 0 5.96 ± 1.88 Z = 2.39 0.02(S)
Vt ml/kg 7.05 ± 0.74 7.03 ± 0.73 Z = 0.05 0.9
RR 12 ± 0 12.38 ± 0.73 Z = 1.4 0.15
PaO2/FiO2 236.3 ± 33.73 233.9 ± 23.05 Z = 0.69 0.49
Inspiratory pressure 10.97 ± 1.88 11.05 ± 1.6 Z = − 0.59 0.56
Time of stay in ICU in days 8.38 ± 1.36 12.03 ± 6.01 Z = 3.04 0.002(S)
Time of mechanical ventilation in days 5.38 ± 1.16 9.14 ± 5.15 Z = 3.90 < 0.001(HS)
Time of starting MV in days 1.71 ± 0.56 1.9 ± 0.82 t = 0.88 0.38
GFR after 48 h of admission (ml/min/1.73 m2) 105.09 ± 11.36 41.69 ± 5.75 t = 25.88 < 0.001(HS)
  1. APACHE II acute physiology and chronic health evaluation II, AKI acute kidney injury, MV mechanical ventilation, GFR glomerular fiteration rate, Vt tidal volume, RR respiratory rate, PaO2/FiO2 arterial oxygen tension/fraction of inspired oxygen, ICU intensive care unit, AKI acute kidney injury, PEEP positive end-expiratory pressure