Articles

Relationship between serum 25-hydroxyvitamin D, total antioxidant capacity and pneumonia incidence, severity and outcome in Nigerian children

The pathologic basis of childhood community-acquired pneumonia (CAP) involves the generation of reactive oxygen species by immune cells leading to cellular damage and lung congestion. Serum antioxidants and vi...

Authors: Bankole Peter Kuti, Alex Ifeoluwa Akinwumi, Demilade Kehinde Kuti and Kazeem Olanrewaju Amoo

Role of CT in differentiation between subtypes of lung cancer; is it possible?

Context and purpose: lung cancer is the second in the incidence rate and the first in death rate in the United States of America in 2017. Its treatment depends upon the tumor staging as well as the histologica...

Authors: Heba Said Gharraf, Sayed Mohamed Mehana and Mostafa Ali ElNagar

Drainage of transudative pleural effusion: how does it affect weaning from mechanical ventilation?

Pleural collections of the transudative type occur frequently in patients who need mechanical ventilation (MV). Treatment of the etiology of the effusion takes a prolonged duration of time. The study intended ...

Authors: Heba Said Gharraf and Alaa El Din AbdAllah

Role of imprint cytology in thoracic endoscopy suite

Fiberoptic bronchoscopy and medical thoracoscopy are basic interventional modalities for the diagnosis of a wide variety of pleuropulmonary diseases. In some cases, we need fast and accurate results for decisi...

Authors: Mohammed Elsaid Hantera, Salwa Atef Ganna, Ayman Mohamed Elsaka and Walaa Mowafy El-Lawaty

Correlation between COVID-19 case fatality rate and percentage of BCG vaccination: is it true the vaccine is protective?

The observations of some recent epidemiological studies offer hope for a reduced impact of COVID-19 for countries which practice universal BCG vaccination policy.

Authors: Aliae A. R. Mohamed Hussein, Marwa Rashad Salem, Samar Salman, A F Abdulrahim, Nasrallah A. Al Massry, Mahmoud Saad, Nesrine Ben Hadj Dahman and Ahmed Negida

The deleterious effects of chronic obstructive pulmonary disease and obstructive sleep apnea: pathophysiology and implications on treatment

Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are both common in the adult population. The coexistence and association of both COPD and OSA have been described as the overlap s...

Authors: Ahmed Gharib

Mean platelet volume change (∆MPV) and red blood cell distribution width (RDW) as promising markers of community-acquired pneumonia (CAP) outcome

Prognostic markers play an essential role in the proper management of community-acquired pneumonia. This research work aimed to evaluate the association of RDW and /or MPV with mortality and morbidity in patie...

Authors: Sahar Farghly, Randa Abd-Elkader, Randa A. El Zohne and Doaa M. Abd El-Kareem

Serum level of transforming growth factor-beta1 in major idiopathic interstitial pneumonia

Different inflammatory cytokines play a role in the mechanism and pathogenesis of fibrosis in idiopathic interstitial pneumonia (IIP). Transforming growth factor-beta1 (TGF-β1) has become a subject of interest...

Authors: Mohamed W. Zakaria, Reem I. El-Korashy, Samah Selim, Ingy Badawy and Kwashi J. Amum

Efficacy of uniportal video-assisted medical thoracoscopy in the management of multiloculated pleural infections: a retrospective study

Pleural infection is a serious medical issue for which the appropriate management is still controversial. Complicated (multiloculated) pleural infection usually requires invasive approach.

Authors: Amr Mounir Shoukri

MicroRNA genetic signature in non-small cell lung cancer (NSCLC) Egyptian patients

Cancer development is associated with deregulated microRNA (miRNA) in body fluids including serum, plasma, and bronchoalveolar lavage (BAL). Early diagnosis and early treatment of lung cancer improve survival ...

Authors: Samar A. Mansour, Amgad A. Farhat, Ayman H. Abd El-Zaher, Adel S. Bediwy, Said M. Abdou, Ayman A. Al Saka and Abdel Aziz A. Zidan

A study of efficacy and safety of tranexamic acid versus iodopovidone in pleurodesis via pigtail catheter in management of recurrent pleural effusion

Researches to detect the ideal agent for pleurodesis are still continuous; iodopovidone is one of the best agents for pleurodesis that are commonly used. Tranexamic acid is also considered by many authors as a...

Authors: Ayman H. Abd El Zaher and Ayman S. El Dib

A preliminary study: MUC5B promoter polymorphism and its association with IPF

The (T) allele of MUC5B gene is strongly correlated with idiopathic pulmonary fibrosis (IPF) and interstitial lung diseases (ILD) related to autoimmune conditions in Caucasians, but no data is available regard...

Authors: Hoda Ali Abu Yusuf, Mohamed Galal, Safy Kaddah, Marwa el Sharkawy, Mohamed Shaaban Mousa and Heba Moussa

Arterial stiffness can occur early in mild-to-moderate chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a well-known respiratory system disorder impacting patient’s morbidity and mortality. Many COPD patients die from cardiovascular diseases. Criteria of arterial s...

Authors: Waleed Mansour, Mohamed El-Shabrawy, Wael A. Khalil, Ahmad S. Eldamanhory and Sameh Embarak

Factors influencing the clinical presentation of hypersensitivity pneumonitis in pigeon breeders in Minia governorate: an Egyptian experience

Bird fanciers’ lung (BFL) is a very famous type of hypersensitivity pneumonitis (HP) produced by airborne exposure to avian antigens. Immunological response and duration of exposure to the avian protein increa...

Authors: Nezar R. Mohamed, Eman Ramadan Ghazawy and Zainab H. Saeed

Intratumoral hyperthermic chemotherapy injection in peripheral non-small cell lung cancer

Intratumoral chemotherapy (ITC) has been used by many groups; the combination of heat and cytotoxic drugs increases the ability to destroy the malignant cells. The aim of this study was to assess the efficacy ...

Authors: Mohamed A. Tohlob, Lucy A. Suliman, Ahmed S. Elmorsy, Mohamed A. Ibrahim and Asem A. Hewidy

Assessment of the role of fractional exhaled nitric oxide as a predictor of airway eosinophilia and corticosteroid responsiveness in patients with chronic cough

Fractional exhaled nitric oxide (FeNO) can be used as a rapid indicator of eosinophilic airway inflammation and steroid responsiveness in patients with bronchial asthma, but this role in chronic cough is still...

Authors: Eman Shebl and Hanaa Abdel-moety

Effect of acute kidney injury on weaning from mechanical ventilation in chronic obstructive pulmonary diseases patients with respiratory failure

Acute kidney injury (AKI) worsens the outcome in mechanically ventilated patients. The occurrence of AKI may have an effect on weaning from mechanical ventilation (MV). The purpose of this work is to study the...

Authors: Ahmed Gouda El-Gazzar, Mahmoud Mohamad El-Salahy, Tarek Samy Essway, Samar Nasef Mohammed and Marwa Elsayed Elnaggar

Prevalence, causes, and chest sonographic findings of bronchiectasis among admitted patients in tertiary care hospital: 10 years’ experience

Bronchiectasis may be associated and/or co-exist with respiratory diseases as bronchial asthma and chronic obstructive pulmonary disease (COPD) or non-respiratory diseases. However, data about this association...

Authors: Aliae Mohamed-Hussein and Hoda Makhlouf

Airflow limitation: is there a correlation between spirometry and quantitative computed tomography measurements in patients with chronic obstructive pulmonary disease?

The ability of computed tomography (CT) in illustrating the pathology of lung parenchyma in patients with chronic obstructive pulmonary disease (COPD) was discussed previously in many articles. However, the co...

Authors: Mohamed Mahros, Hossam Hosny, Ayman Ismail and Heba Moussa

Vocal cordopathy consequent to bronchial asthma inhalation therapy

Vocal cords signify an imperative lane for air flow in and out of the respiratory tract along with a phonetic role. So, the aim of this work is to assess the impact of habitual versus occasional utilization of...

Authors: Ahmed Mohammed Abumossalam, Hanan Abdelsattar Ahmed, Omar Mohamed Ibrahim, Talal Mohamad Saad Algreisy and Abdullah Mohmad Al-Shenqiti

Platelet count as a predictor of outcome of hospitalized patients with community-acquired pneumonia at Zagazig University Hospitals, Egypt

Platelets play an essential role in both coagulation system and the host immune defenses against infection including community-acquired pneumonia (CAP). This work aimed to study the possibility of using platel...

Authors: Adel H. A. Ghoneim, Mohammad A. Mohammad, Mohammad A. Elghamrawy and Sameh Embarak

Outcome of ultrasound-guided, single session pleurodesis in malignant pleural effusion

Chemical pleurodesis is frequently indicated to relieve symptoms imposed by large/recurrent malignant pleural effusion (MPE). Traditionally, a drain is left in the pleural space till the cessation of fluid acc...

Authors: Khalil M. Magdy and Ezzelregal G. Hieba

Effect of incentive spirometer exercise on pulmonary functions in children with spastic cerebral palsy

Authors: Mahmood Dhahir Al-Mendalawi

Relations between serum and pleural fluid biomarkers: a new look of an old concept

Although cytological examination of pleural fluid samples can simply diagnose malignant pleural effusion (MPE), this test has many limitations. There are no established biomarkers for accurate diagnosis of MPE...

Authors: Sabah Ahmed Hussein and Maha Yousif Elhefnawy

Awareness of obstructive sleep apnea among critical care physicians in Sharkia Governorate, Egypt

Patients with symptoms of obstructive sleep apnea (OSA) present to nearly all physicians irrespective of their specialties. A basic knowledge of OSA is considered essential to identify those patients for appro...

Authors: Sameh Embarak, Lamiaa G. Zake, W. Abd-El-Azem and Ashraf E. Sileem

Role of different imaging modalities in the evaluation of normal and diseased thymus

The appearance of the thymus on imaging studies showed great variability. Thymus imaging is a great challenge. This cross-sectional prospective study investigated the diagnostic value of different imaging moda...

Authors: S. A. Hussein, Y. Y. Sabri, M. A. Fouad, H. H. Al-Zawam and N. M. Mohamed

Role of I-scan technique in screening for lung cancer in smokers with positive sputum cytology

Lung cancer has a very poor prognosis and high mortality. Positive sputum for malignant and/or atypical cells warrants the need for fibreoptic bronchoscopy. White light bronchoscopy (WLB) is usually unable to ...

Authors: Ahmed Mohamed Abdelhady and Dina Mohamed Mohamed Abdallah

The clinical utility of joined detection of cancer ratio, cancer ratio plus, Interferon gamma (IFN-ϒ) & Carcinoembryonic antigen (CEA) in differentiating lymphocytic pleural effusions

The differentiation between malignant (MPE) and tuberculous (TPE) pleural effusions should be considered in any patient with an exudative lymphocytic pleural effusion. A rapid precise diagnosis is valuable as ...

Authors: Dalia E. ElSharawy, Maha M. Hagras and Rasha A. Khedr

Endobronchial ultrasound guided Echo Tip Ultra HD 22G needle versus Echo Tip Pro Core HD 22G needle in diagnosis of mediastinal lesions

Convex probe endobronchial ultrasound is a minimally invasive technique used for performing real-time transbronchial needle aspiration of enlarged hilar and mediastinal lymph nodes and could be used for diagno...

Authors: Sabah Ahmed Hussein, Alaa Eldein Omar Shalaby, Khaled Mahmoud Kamel, Amal Ahmad Hareedy and Hoda Mohamed Mahmoud Abdelhameed

Tracheal bullet excreted with the stool: a rare course of events in airway gunshot injury

Over the past 10 decades, only five cases have been published of firearm injuries of the chest with conservative management, who in the follow-up expectorated the bullet. We report the first case in the histor...

Authors: Nasir U. Din Wani, Tasneem Muzaffar, Syed A. Hussain, Yasir Wani, Danish Zahoor, Aaliya Wani and Farhana Bashir

Spontaneous resolution of persistent lymphadenitis: a case of Kikuchi–Fujimoto disease

Cervical lymphadenopathy is common in all age groups. Persistently enlarged cervical lymph nodes often pose a diagnostic challenge and necessitate focused clinical evaluation with targeted investigations. Path...

Authors: Divya Ramachandran, Rajesh Venkitakrishnan, Jolsana Augustine and Melcy Cleetus

Study of upper airway inflammation in patients with obstructive sleep apnea–hypopnea syndrome

Pharyngeal lavage was reported as a novel technique for noninvasive assessment of inflammation of the pharynx.

Authors: Enas E. Mohamed, Ayman I. Baess and Yasser M. Eldowik

Original, simplified, and modified pulmonary embolism severity indices in risk stratification of pulmonary embolism

Acute pulmonary embolism (PE) is a potentially fatal disease. Prognostic assessment is needed for proper management. Several prognostic models have been proposed.

Authors: Maha Yousif and Sabah A. Hussein

Effect of incentive spirometer exercise on pulmonary functions in children with spastic cerebral palsy

Spastic cerebral palsy (CP) patients have lower pulmonary functions than normal healthy individuals as they usually have decreased chest wall mobility, deviation of optimal chest wall structure, and weak respi...

Authors: Magda Y. Elseify, Dina A. Ramadan and Sally R. Ishak

Pattern of chest diseases among addicts in Poison Control Center of Ain Shams University Hospitals

Drug addiction results in serious pulmonary complications. Thoracic complications of drug addiction vary depending on the type and the route of administration of the drug that has been abused.

Authors: Aya M. AbdelDayem, Mahmoud L. Sakr, Nehad M. Osman, Maryam A. Abd El Kader and Sherehan EL Sayed Abd El-Aaty

Ultrasonographic evaluation of the diaphragm

Ultrasonography is a promising technique for structural and functional evaluation of the diaphragm. It is accurate, reproducible, and portable with no ionizing radiation. Multiple studies have reported ultraso...

Authors: Youssriah Y. Sabri, Sabah A. M. Hussein, Ahmed A. M. Baz and Amal A. M. Aglan

Reliability of ultrasound in confirming endotracheal tube placement as a new and fast tool

Chest ultrasound has been an important tool for the diagnosis of many chest diseases, and, recently, it became an important tool for confirmation of the site of endotracheal tube placement. In our study, we us...

Authors: Mohammad W. S. Moghawri, Niveen E. Zayed and Dalia A. Ibrahim

Histopathological findings in patients with refractory nonfibrotic hypersensitivity pneumonitis

The course of hypersensitivity pneumonitis (HP) is characterized by variable patterns of disease progression. Refractory HP is defined as poor or lack of response to different modalities of treatment with wors...

Authors: Yosri M. K. Akl, Raef H. Emam, Ahmed H. El-Habashi, Mohamed S. Ismail and Hossam Abdallah

Pulmonary rehabilitation outcome in chronic obstructive pulmonary disease patients with a different body composition

Change in body composition is commonly present in chronic obstructive pulmonary disease (COPD) patients.

Authors: Laila A. Alsharaway

Cardiovascular comorbidities associated with patients with chronic obstructive pulmonary disease – a hospital-based study

Most patients with chronic obstructive pulmonary disease (COPD) have cardiovascular comorbidities (CVD), which significantly contribute to the mortality and morbidity in these patients.

Authors: Amit S. Gupta, Venkitakrishnan Rajesh and Ponneduthamkuzhy James

Does vitamin D deficiency worsen the clinical and functional parameters of stable chronic obstructive pulmonary disease patients?

There is not much data about the effect of deficient vitamin D on stable chronic obstructive pulmonary disease (COPD) patients and its relation to the disease severity.

Authors: Esmat A. Abd Elnaby, Samah S. Abd Elnaiem, Amira I. Mostafa, Dina Sabry and Mohamed K. Haswa

Airway inflammatory biomarkers in different asthma phenotypes

Asthma is a diverse disease with various phenotypes. Correlation of clinical asthma phenotypes with their underlying inflammatory biomarkers could help tailor asthma management and in turn improve the patient’...

Authors: Amal M. Osman and Afaf M. Elsaid

Assessment of serum interleukin 6 level in patients with chronic obstructive pulmonary disease: is it related to disease severity?

Chronic obstructive pulmonary disease (COPD) is a common disease that can be prevented and even treated. It leads to high morbidity and mortality rates. Pro-inflammatory cytokines and oxidative radicals were f...

Authors: Esmat A. Abd Elnaby, Samah S. Abd Elnaiem, Amira I. Mostafa, Dina Sabry, Alshaimaa Rezk I R Alnaggar and Mohamed K. Haswa

The impact of admission blood glucose level on patients with community-acquired pneumonia

Pneumonia is one of the most common diseases with a high hospitalization rate. Many studies have suggested that there is a correlation between pre-existing diabetes and the alterations in serum glucose levels ...

Authors: Tamer M. Ali, Hala M. Salem and Dina R. Sultan

Study of the prevalence and pattern of fungal pneumonias in respiratory intensive care units

Fungal pneumonia is an infectious process in the lung caused by one or more endemic or opportunistic fungi. Fungal infection occurs following the inhalation of spores, after the inhalation of conidia, or by th...

Authors: Mona M. Ahmed, Ayman A. Farghaly, Riham H. Raafat and Waleed M. Abd Elsattar

Role of lactate dehydrogenase and other biomarkers in predicting prognosis of community-acquired pneumonia

An increase in serum lactate dehydrogenase (LDH) activity is commonly taken to support the presumptive diagnosis of some lung diseases and a variety of extrapulmonary disorders, but the role of LDH as an early...

Authors: Rasha M. Hendy, Mona A. Elawady and Heba M. Abd EL Kareem

Delay in the diagnosis and management of tuberculosis among patients in the Suez Canal Area

Delayed diagnosis of tuberculosis (TB) can enhance the transmission of infection and worsen prognosis.

Authors: Noha M. Abu Bakr Elsaid, Amany H. Refaat, Lamiaa A. Fiala and Eman R. Hamed

Clinical outcome of weaning in mechanically ventilated patients with chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) represents a significant reason for mortality and morbidity worldwide that induces a high socioeconomic burden, with exacerbations necessitating mechanical ventilat...

Authors: Suzan Salama Sayed, Khalid Hussein Ahmed, Sayed Abdelsabour Kinawy and Islam Galal Sayed

Impulse oscillometry usefulness in small-airway dysfunction in asthmatics and its utility in asthma control

Small-airway affection and its relation to clinical status in asthmatic patients became an increasing interest during the last decade. Spirometry is a basic diagnostic tool for measuring pulmonary function in ...

Authors: Ragia S. Sharshar

A study of plasma copeptin level as a predictor of severity during acute exacerbation of bronchial asthma

An exacerbation of asthma is an episode, characterized by a progressive increase in one or more typical asthma symptoms (shortness of breath, wheezing, cough, and chest tightness).

Authors: Ahmed G. El Gazzar, Khaled M. Belal, Tarek S. Essawy and Neveen M. Abd-Elfattah