Articles

Prevalence of obstructive sleep apnea among patients with chronic obstructive pulmonary disease

The conjunction of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as overlap syndrome (OS). The coexistence of these diseases has cardiovascular morbidity and mortality...

Authors: Osama Ibrahim Mohammad, Ahmed Gouda Elgazzar, Shymaa Mohammad Mahfouz and Marwa Elsayed Elnaggar

Evaluation of the impact of COPD severity grading and oxygen saturation on the retinal nerve fiber layer thickness and subfoveal choroidal thickness in COPD patients

Retinal and choroidal blood vessels are involved in many systemic diseases because they are complex vascular systems. Chronic obstructive pulmonary disease is considered as an inflammatory disease that affects...

Authors: Noha Othman Ahmed, Yasmine Maher Shaaban and Hieba Gamal Ezzelregal

Post-COVID depression among a sample of Egyptian patients and its associated factors

Depression is classified as a mood disorder. It may be described as feelings of sadness, loss, or anger that interfere with a person’s everyday activities. Nowadays, we are in COVID-19 pandemic. From practice ...

Authors: Hieba Gamal Ezzelregal, Azza Mohammed Hassan, Rehab Serag Mohamed and Noha Othman Ahmed

Intracavitary anaesthesia for medical thoracoscopy procedural pain: the CAMP randomised trial

Medical thoracoscopy (MT) under conscious sedation can be a painful procedure. A pilot study reported reduction in procedural pain with lidocaine application via chest tube before procedure. This study aimed a...

Authors: Ahmed Mohamed Abdelhady, Mohamed Gadallah, Moustafa Shaheen, Sahar Mourad and Maged Hassan

The growth factor/cytokine midkine may participate in cytokine storm and contribute to the pathogenesis of severe acute respiratory syndrome coronavirus 2-infected patients

The current coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged in Wuhan, China, and has rapidly become a global challenge, creating ...

Authors: Sema Ketenci and A. Şükrü Aynacıoğlu

Impact of air pollution and smoking on COVID-19: a review

The 21st century already witnessed many deadly epidemics and pandemics. The major ones were respiratory tract infections like SARS (2003), H1N1 (2009), MERS (2012) and the most recent pandemic COVID-19 (2019)....

Authors: Vijaytha Vijayakumar, A. Sabu and M. Haridas

Chronic obstructive pulmonary disease in non-smokers: role of oxidative stress

A striking feature of chronic obstructive pulmonary disease (COPD) is its inability to resolve after cigarette smoke exposure has ended, which has contributed to the possibility that the disease could also be ...

Authors: Zainab H. Saeed, Mohamed A. E. Abd El Hakim and Nezar R. Mohamed

Polysomnographic and clinical characteristics of positional obstructive sleep apnea patients

Obstructive sleep apnea is a condition characterized by the complete or partial obstruction of the upper airway during sleep. This study aimed to compare the clinical and polysomnographic characteristics of ou...

Authors: Seda Beyhan Sagmen and Sevda Cömert

Inhaled corticosteroid response in smoker versus non-smoker asthmatic patients: a cross-sectional study

Asthmatic smokers are a distinct phenotype of asthma. There is a lack of specific information about the treatment of asthma in smokers. The purpose of this study was to compare the effects of inhaled corticost...

Authors: Sahar Farghly Youssif, Atef Farouk El-Karn, Mahmoud Farouk Sherif, Mohamed I. Seddik, Safaa Abdelgayed and Mohammed F. Abdelghany

Trends in pattern of tuberculosis in Sharkia Governorate at Ministry of Health and Population Chest Hospitals from 2016 to 2019

Tuberculosis is a communicable disease that is one of the leading cause of death from a single infectious agent (ranking above human immunodeficiency virus/acquired immunodeficiency syndrome). The aim of this ...

Authors: Mohamed El-Shabrawy, Dalia A. Ibrahim, Mohammad Walaa, Mona S. Hamed, Ahmed A. Abdelmoaty, Maher El-Shafei and Maha E. Alsadik

Association between house dust mites sensitization and level of asthma control and severity in children attending Mansoura University Children’s Hospital

House dust mites (HDM) are considered as a major source of indoor aeroallergen all over the world that precipitate allergic reactions including rhinoconjunctivitis, food allergy, atopic dermatitis, and allergi...

Authors: Nahla Mohamed Okasha, Amr Ali Sarhan and Engy Osman Ahmed

Pneumomediastinum, pneumopericardium, and subcutaneous emphysema—a rare complication in COVID-19 infection

Coronavirus disease 2019 (COVID-19) has become a global pandemic and is posing a serious public health problem for almost all countries. Spontaneous pneumomediastinum, a rare condition, is usually seen in pati...

Authors: Archana Baburao, Rinki Das and Shylaja Shyamsunder

Respiratory coinfections in COVID-19 patients evaluated by BioFire Pneumonia Panel

Routine administration of antibacterials in patients with Covid-19 has been a subject of debate, with no solid data about the true prevalence of respiratory coinfections in Covid-19 patients in different geogr...

Authors: Hebatallah Hany Assal, Maged Salah, Ayman Kamal Ibrahim, Mostafa Alfishawy, Rawia Khater, Hossam Hosny Masoud, Ahmed Monier Eldemerdash and Mohamed Ali AbdelHalim

Increasing fetal hemoglobin as a possible key for improvement of hypoxia and saving last breath in COVID-19 patient: “postulating a hypothesis”

COVID-19 patients normally experience mild cold-like symptoms that progress from the early viral response phase through the lung phase to the hyper-inflammation phase. Acute respiratory distress syndrome (ARDS...

Authors: Muhamed A. Abdelzaher, Ashraf E. S. Ibrahim and Essamedin M. Negm

Elimination of nasal obstruction improves pulmonary functions and oxygenation

Nasal obstruction is a significant medical problem. This study aimed to examine the effect of nasal obstruction and nasal packing on arterial blood gases and pulmonary function indices, and the impact of the e...

Authors: Eman Sobh, Fatma Elhussieny and Taghreed Ismail

The role of ultrasound-guided transthoracic Tru-Cut core biopsy in the diagnosis peripheral thorax lesion

The nature of opaque lesions such as effusions, atelectasis, masses, and consolidations can be clarified by sonography. This study investigated the sensitivity and accuracy of ultrasound-guided percutaneous co...

Authors: Maha Fathy Mohamed, Nabila Ibraheem Laz, Khaled Mahmoud Kamel and Raghda Yaser Mahmoud

Patient-ventilator asynchrony as a predictor of weaning failure in mechanically ventilated COPD patients

Patient-ventilator asynchrony is a common problem in mechanically ventilated patients. It is associated with adverse effects including increased work of breathing, patient discomfort, increased need for sedati...

Authors: Samiaa H. Sadek, Maha M. El-kholy, Marwa S. Abdulmoez and Reham M. El-Morshedy

Prognostic biomarkers in COVID-19 infection: value of anemia, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and D-dimer

Being highly infectious disease, COVID-19 exhausts most of efficient healthcare systems worldwide. Simple and rapid risk stratification methods are mandatory to recognize severe patients. This study aims to hi...

Authors: Maiada K. Hashem, Eman M. Khedr, Enas Daef, Aliae Mohamed-Hussein, Ehab F. Mostafa, Sahar M. Hassany, Hanan Galal, Shimaa Abbas Hassan, Islam Galal, Mariam Taher Amin and Hebatallah M. Hassan

Double hitch stitch is a novel technique for fixation of tracheal stent in a case of tracheoesophageal fistula: a case report

Caudal tracheal stent migration can be potentially life threatening by causing distal luminal obstruction. We present a rare double hitch stitch procedure (for prevention of migration of tracheal stent), which...

Authors: Sameer A. Arbat, Parimal S. Deshpande and Sweta R. Chourasia

Dynamic role of LMW-hyaluronan fragments and Toll-like receptors 2,4 in progression of bleomycin induced lung parenchymal injury to fibrosis

Pulmonary fibrosis (PF) is a progressive and lethal lung disease of elderly whose incidence has been increasing following the Covid-19 pandemic caused by severe acute respiratory syndrome corona virus 2 (SARS-...

Authors: Apoorva Pandey, Ritu Kulshrestha and Surendra Kumar Bansal

Diagnostic performance of lung volumes in assessment of reversibility in chronic obstructive pulmonary disease

Reversibility measured by spirometry in chronic obstructive pulmonary disease (COPD) is defined as an increase in forced expiratory volume in first second (FEV1) that is both more than 12% and 200 mL above the...

Authors: Gamal Agmy, Manal A. Mahmoud, Azza Bahaa El-Din Ali and Mohamed Adam

Pulmonary function before and after surgical correction of scoliosis

As one of the restrictive lung diseases, scoliosis can be treated by surgical intervention to enhance the pulmonary function of that group of patients. The purpose of the study was to determine the effects of ...

Authors: Mona Mansour Ahmed, Hesham Atef Abdelhalim and Reham Mohammed Mohammed Elamir

Retrospective study of pulmonary and extrapulmonary tuberculosis cases in Giza Governorate during the period of 2014–2018

Tuberculosis in Egypt is a main public health problem. Egypt is categorized among the mid-level incidence countries. The objective of this work is to study the epidemiology of TB in Giza Governorate during the pe...

Authors: Amany Rabea Abd El Malik, Amany Ezz Elarab Abd El Wahab and Heba H. Eltrawy

Systemic AL amyloidosis presenting with diffuse alveolar septal involvement and respiratory failure: a case report and review of the literature

Amyloidosis is the extracellular deposition of amyloid fibril protein in any tissue or organ. The clinical manifestations of pulmonary amyloidosis are variable and without specific symptoms. We report a rare c...

Authors: Hamdy Ali Mohammadien, Shimaa Nour Morsi and Moaz Atef Al Shahat

Correlation between nocturnal oxygen desaturation and glycemic control in diabetic patients with obstructive sleep apnea

Nocturnal hypoxia occurring in obstructive sleep apnea (OSA) is associated with different metabolic disturbances. The present study aims to correlate between nocturnal oxygen desaturation and levels of glycemi...

Authors: Amr Mounir Shoukri

Modified thoracoscopic pleural cryo-biopsy in diagnosis of exudative pleural effusion of undetermined etiology

Rigid thoracoscopy is the gold standard tool for diagnosing exudative pleural effusion, but sometimes it is difficult to obtain sufficient biopsies using the conventional forceps. This study evaluated the effi...

Authors: Ayman Ibrahim Baess, Essam Gouda Hassanein, Mohamed Al Saeed Emara and Heba Ahmed Eshmawey

Role of detection of lipoarabinomannan (LAM) in urine for diagnosis of pulmonary tuberculosis in HIV patients: Egyptian experience

Tuberculosis remains a worldwide problem fueled by the HIV epidemic. TB infection impacts HIV progression and mortality even with treatment. Egypt has increasing HIV prevalence, although still in low prevalent...

Authors: Nagwa Elhalawany, Nessrin Shalaby, Amal Fathy, Ahmed S. Elmorsy, Mohamed Zaghloul, Heba El-shahawy and Asem A. Hewidy

The value of endobronchial cryotherapy in the management of malignant endobronchial obstruction in patients with inoperable NSCLC: a prospective analysis of clinical and survival outcomes

Malignant endobronchial obstruction (MEBO) is the most debilitating complication in non-small cell lung cancer (NSCLC). The therapeutic role of cryotherapy and its impact on survival has not been well addresse...

Authors: Alaa Rashad, Mohamed Shahat Badawy, Mohammed Mustafa Ali, Haggagy Mansour and Mohamed Abdel-Bary

Evaluation of the efficacy of pirfenidone in progressive chronic hypersensitivity pneumonitis

The present data about the treatment of progressive CHP are few and largely based on observational studies and expert opinion. It is suggested that pirfenidone may slow disease progression in cases of CHP as i...

Authors: Eman Shebl and Tarek Hamdy

High flow nasal cannula oxygen and non-invasive mechanical ventilation in management of COVID-19 patients with acute respiratory failure: a retrospective observational study

High flow nasal cannula oxygen (HFNCO) is a relatively new technique used to deliver oxygen in respiratory failure patients. This retrospective study is aiming to assess the role and benefits of using HFNCO co...

Authors: Amr Mounir Shoukri

Prognostic biomarkers in predicting mortality in respiratory patients with ventilator-associated pneumonia

Ventilator-associated pneumonia (VAP) is the most common nosocomial infection. Red cell distribution width (RDW) and neutrophil-lymphocyte ratio (NLR) are prognostic factors to mortality in different diseases....

Authors: Nermeen A. Abdelaleem, Hoda A. Makhlouf, Eman M. Nagiub and Hassan A. Bayoumi

Antibiograms of intensive care units at an Egyptian tertiary care hospital

Intensive care unit (ICU) infection management is a growing challenge, and physicians should have regularly updated antibiograms. The aim of this study was to find out the prevalence of pathogens and to determ...

Authors: Essamedin M. Negm, Sherif M. S. Mowafy, Ahmad A. Mohammed, Marwa G. Amer, Ahmed E. Tawfik, Ashraf E. S. Ibrahim and Tarek H. Hassan

Impact of COVID-19 infodemic on psychological wellbeing and vaccine hesitancy

With COVID-19 pandemic, the world has witnessed a scenario that is unique compared to any other such pandemic that the world has grappled with. This is primarily owing to the parallel infodemic that the popula...

Authors: Janmejaya Samal

CO-RADS versus CT-SS scores in predicting severe COVID-19 patients: retrospective comparative study

The role of CT in assessing and plotting viral pulmonary affection land marking is its potential among other investigation tools, and the aim of the study was to compare the ability of two different CT-based s...

Authors: Niveen E. Zayed, Manar A. Bessar and Samah Lutfy

Level of asthma control and mental health of asthma patients during lockdown for COVID-19: a cross-sectional survey

Lockdown has been enforced globally to curb the spread of SARS-CoV-2. Patients with uncontrolled asthma are at risk of severe illness from COVID-19, highlighting the priority of adequate asthma control during ...

Authors: Dina S. Sheha, Asmaa S. Abdel-Rehim, Osama M. Abdel-Latif, Maryam A. Abdelkader, Riham H. Raafat, Sarah A. Sallam and Nayera S. Mostafa

Correction to: A review of the genome, epidemiology, clinical features, prevention, and treatment scenario of COVID-19: Bangladesh aspects

An amendment to this paper has been published and can be accessed via the original article.

Authors: Abdullah Al Noman, Md. Shofiqul Islam, Samiron Sana, Prapti Mondal, Rima Islam Meem, Sohel Rana, Debashish Mondol, Manoshi Sana, Sheikh I. Hossain, Taufique Joarder and Kishor Mazumder

Determinants of persistent post-COVID-19 symptoms: value of a novel COVID-19 symptom score

Being a newly emerging disease, little is known about its long-lasting post-COVID-19 consequences. The aim of this work is to assess the frequency, patterns, and determinants of persistent post-COVID-19 sympto...

Authors: Islam Galal, Aliae A. R. Mohamed Hussein, Mariam T. Amin, Mahmoud M. Saad, Hossam Eldeen E. Zayan, Mustafa Z. Abdelsayed, Mohamed M. Moustafa, Abdel Rahman Ezzat, Radwa E. D. Helmy, Howida K. Abd_Elaal, Nasrallah A. Al Massry, Mohamed A. Soliman, Asmaa M. Ismail, Karima M. S. Kholief, Enas Fathy and Maiada K. Hashem

ABO groups can play a role in susceptibility and severity of COVID-19

A few people infected by the coronavirus become seriously ill, while others show little to no signs of the symptoms, or are asymptomatic. Recent researches are pointing to the fact that the ABO blood group mig...

Authors: S. Samra, M. Habeb and R. Nafae

A review of the genome, epidemiology, clinical features, prevention, and treatment scenario of COVID-19: Bangladesh aspects

The ongoing acute respiratory disease pandemic termed COVID-19 caused by a newly emerged coronavirus has jeopardized the world’s health and economic sectors. As of 20 July 2020, the virus now known as SARS-CoV...

Authors: Abdullah Al Noman, Md. Shofiqul Islam, Samiron Sana, Prapti Mondal, Rima Islam Meem, Sohel Rana, Debashish Mondol, Manoshi Sana, Sheikh I. Hossain, Taufique Joarder and Kishor Mazumder

The possible puzzles of BCG vaccine in protection against COVID-19 infection

The paper aimed to analyze and evaluate the present literature data on the clinical effectiveness of using the bacillus Calmette–Guérin (BCG) vaccine in protecting against the novel coronavirus disease 2019 (C...

Authors: Basheer Abdullah Marzoog and Tatyana Ivanovna Vlasova

Non-invasive IGFBP1, IGFBP2 biomarkers as predictors and outcomes of usual interstitial pneumonia (UIP) therapeutic response

Usual interstitial pneumonia (UIP) is a fatal disease that is associated with poor prognosis and survival. Several growth factors such as IGFs (insulin-like growth factors) and IGFBPs (insulin-like growth fact...

Authors: M. Habeb, S. Embarak, A. Fathy and M. Zalat

Interleukin-6 and C-reactive protein/albumin ratio as predictors of COVID-19 severity and mortality

Coronavirus disease 2019 (COVID-19) was announced in early December 2019. The pandemic situation is declared. This study aimed to evaluate the role of biomarkers in estimating the severity and predicting the p...

Authors: Mohamed El-Shabrawy, Maha E. Alsadik, Maher El-Shafei, Ahmed A. Abdelmoaty, Ahmed S. Alazzouni, Marwa M. Esawy and Marwa A. Shabana

Prevalence of asthma—chronic obstructive pulmonary disease overlap in patients with airflow limitation

Asthma-COPD overlap (ACO) according to GINA and GOLD is not a single disease and is described by persistent airflow limitation with several features usually associated with asthma and several features usually ...

Authors: Ahmed Youssef Shabaan, Rasha Galal Daabis, Ahmed Mohamed Abdelhady and Dina Hassan Ibrahim

Acute kidney injury in hospitalized patients with COVID-19 (retrospective study)

The World Health Organization (WHO) has named the virus as 2019 novel coronavirus on January 12, 2020, and has declared a public health emergency globally on January 30, 2020. The epidemic started in Wuhan, Ch...

Authors: Haitham A. Azeem, Hytham Abdallah and Mohamad M. Abdelnaser

Environmental hazards and demographic and clinical data of childhood interstitial lung diseases in a tertiary institute in Egypt

The incidence of childhood interstitial lung diseases increased in the last years in Egypt. Changes in environmental and climatic conditions may be contributing factors. Also, raising birds at home increased i...

Authors: Sally Raafat Ishak, Azza Mohammed Hassan and Terez Boshra Kamel

Sleep quality in stable chronic obstructive pulmonary disease patients in Zagazig University Hospitals, Egypt

Chronic obstructive pulmonary disease (COPD) causes changes in sleep quality with accompanied nocturnal drops in oxygen saturation leading to cardiac dysrhythmias, pulmonary hypertension, and more arousal. How...

Authors: Adel H. A. Ghoneim, Mohamed S. El-Gammal, Yasmeen R. Ahmed and Doaa M. Gad

A prospective observational study on acute exacerbation of chronic obstructive pulmonary disease in pulmonology department of tertiary care hospital

Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveola...

Authors: Sreenu Thalla, Akhila Yerubandi, Sk. Hafeezunnisa, Sk. Jareena and Sivakshari Makkapati

Study of cognitive functions in major idiopathic interstitial pneumonias

Cognitive dysfunction in idiopathic interstitial pneumonia (IIP) is an important clinical co-morbidity that is associated with impaired lung function. The aim of the work is to assess cognitive function in major ...

Authors: Mohamed W. Zakaria, Reem I. El-Korashy, Mostafa O. Shaheen, Samah Selim and Kwashi J. Amum

Ultrasound as a bedside tool for diagnosis of post-intubation tracheal stenosis

Screening of post-intubation stenosis can allow early diagnosis, early management of stenosis, and possible prevention of progress. Fiberoptic bronchoscope is the gold standard for diagnosis of tracheal stenos...

Authors: Shereen Farghaly, Ashraf Zin El-Abdeen, Lamiaa H. Shaaban, Hossam El-Deen Galal M. El-Malah and Maida Kamal

Leukocyte count in COVID-19: an important consideration

Authors: Samah Selim