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Table 3 Comparison between groups according to pulmonary functions tests, hormonal profile, diaphragmatic excursion, and diaphragmatic thickness

From: Diaphragmatic ultrasound and pulmonary functions evaluation in thyroid patients: a case-control study

 

Hyperthyroidism (n = 40)

Hypothyroidism (n = 40)

Control (n = 40)

ANOVA

p value

Pulmonary function test

VC %

94.15 ± 4.31

76.90 ± 7.46a

102.65 ± 7.63ab

65.496

<0.001**

FVC%

90.95 ± 4.47

72.45 ± 7.46a

93.80 ± 3.56b

76.721

<0.001**

FEV1%

81.70 ± 14.54

72.25 ± 11.65a

90.55 ± 2.95ab

11.869

<0.001**

FEVI/FVC

87.15 ± 5.74

78.77 ± 5.87a

92.36 ± 4.85ab

26.074

<0.001**

FEF25–75%

72.30 ± 12.47

72.00 ± 8.01

82.70 ± 9.54ab

6.023

<0.001**

Hormonal profile

TSH uIU/mg

0.04 ± 0.06

25.41 ± 9.50a

2.48 ± 1.00ab

108.271

<0.001**

Free T3

9.29 ± 2.48

1.58 ± 0.79a

4.49 ± 0.67ab

105.970

<0.001**

Free T4 pmol/l

29.40 ± 4.57

4.37 ± 2.46a

15.75 ± 1.76ab

263.809

<0.001**

Diaphragmatic Excursion

Rt tidal

1.61 ± 0.34

1.42 ± 0.29a

2.17 ± 0.27ab

28.321

<0.001**

Rt deep

5.63 ± 0.50

5.07 ± 0.72a

6.63 ± 0.33ab

35.937

<0.001**

Rt sniff

2.67 ± 0.27

2.15 ± 0.26a

2.89 ± 0.19ab

41.277

<0.001**

Lt tidal

1.42 ± 0.32

1.30 ± 0.30a

2.18 ± 0.31ab

39.774

<0.001**

Lt deep

5.41 ± 0.55

4.78 ± 0.66a

6.41 ± 0.41ab

37.722

<0.001**

Lt sniff

2.48 ± 0.23

2.01 ± 0.31a

2.69 ± 0.23ab

29.825

<0.001**

Diaphragmatic thickness

Rt end tidal insp

2.83 ± 0.20

2.69 ± 0.31

2.89 ± 0.14b

4.472

0.021*

Rt end tidal exp

1.69 ± 0.27

1.81 ± 0.19

1.67 ± 0.22

1.557

0.107

  1. F one-way analysis of variance
  2. **p value < 0.001 HS
  3. Post hoc: a, significant difference with hyperthyroidism; b, significant difference with hypothyroidism
  4. BMI body mass index, VC vital capacity, FVC forced vital capacity, FEV1 forced expiratory volume in 1st second, FEF25–75% forced expiratory flow rate 25–75%, R right, Lt left, TSH thyroid stimulating hormone, T3 free triiodothyronine, and T4 free thyroxin