Table 6 ROC curve analysis of KL6, WBCs, ESR, and CRP between stable and exacerbation
From: Serum Krebs von den Lungen (KL-6) level as a marker of exacerbation of interstitial lung diseases
AUC | p value | Sensitivity | Specificity | Positive predicted value (PPV) | Negative predicted value (NPV) | Confidence interval (CI 95%) | Cut-off point | |
|---|---|---|---|---|---|---|---|---|
KL6 | 0.977 | < 0.001 | 97.9% | 62% | 72.06 | 96.88 | 0.943–1 | 187.5 |
WBC | 0.779 | < 0.001 | 70.2% | 69.2% | 69.31 | 69.7 | 0.674–0.883 | 8.55 |
ESR | 0.504 | 0.124 | 53.2% | 67.7% | 62.35 | 59.13 | 0.362–0.646 | 25 |
CRP | 0.825 | < 0.001 | 93.6% | 69.2% | 75 | 90.7 | 0.702–0.948 | 3 |