From: Interleukin-6 and C-reactive protein/albumin ratio as predictors of COVID-19 severity and mortality
Parameters | Non-severe (no.: 99) | Severe (no.: 17) | P |
---|---|---|---|
Age, years | 36 [21-77] | 54.5 [20-88] | 0.001* |
Sex, male | 51 (51.5) | 12 (70.6) | 0.15 |
Smoking | 6 (6.1) | 4 (23.5) | 0.018* |
Symptoms | |||
• Fever | 85 (85.9) | 16 (94.1) | 0.35 |
• Fatigue | 22 (22.2) | 5 (29.4) | 0.52 |
• Bone ache | 17 (17.2) | 4 (23.5) | 0.53 |
• Anosmia | 55 (55.6) | 4 (23.5) | 0.015* |
• Nausea or vomiting | 3 (3) | 1 (5.9) | 0.55 |
• Diarrhea | 5 (5.1) | 2 (11.8) | 0.28 |
• Abdominal pain | 9 (9.1) | 3 (17.6) | 0.29 |
• Sore throat | 9 (9.1) | 3 (17.6) | 0.29 |
• Cough | 72 (72.7) | 12 (70.6) | 0.86 |
• Dyspnea | 4 (4) | 10 (58.8) | < 0.0001* |
• Chest tightness | 5 (5.1) | 7 (41.7) | < 0.0001* |
Co-morbidities | |||
• Diabetes | 8 (8.1) | 5 (29.4) | 0.01* |
• Hypertension | 12 (12.1) | 6 (35.3) | 0.015* |
• Coronary heart disease | 2 (2) | 3 (17.6) | 0.003* |
• Chest diseases | 5 (5.1) | 4 (23.5) | 0.009* |
• Thyroid diseases | 0 (0) | 1 (5.9) | 0.015* |
Vital signs | |||
• Respiratory rate, breaths/min | 22 [20-23] | 23 [21-30] | < 0.0001* |
• Oxygen saturation, % | 95 [94-97] | 87 [72-94] | < 0.0001* |
Outcome | |||
• Mortality | 0 (0) | 8 (47.1) | < 0.0001* |
Laboratory parameters | |||
• IL-6, pg/mL | 14.5 [6.8-47.5] | 55.9 [20.5-123.5] | < 0.0001* |
• CRP, mg/L | 20.5 [6-73] | 46 [18.5-183] | < 0.0001* |
• Albumin, g/dL | 4 [3-5.3] | 3.5 [2.8-5] | 0.024* |
• CRP/albumin ratio | 5.1 [1.6-18.7] | 14.1 [5.8-48.2] | < 0.0001* |