Table 3 Comparison of the clinical presentation outcomes, respiratory function tests, arterial blood gases, and the mean Karnofsky performance score for group A subgroups (main bronchi and lobar bronchi obstruction)
Variable | Main bronchi (Group A1) | Lobar bronchi (Group A2) | P values I & II | P values I & III | P values II & IV | P valued III & IV | |||
|---|---|---|---|---|---|---|---|---|---|
Pre-cryotherapy (I) (n=21) | Post-cryotherapy (II) (n=21) | Pre-therapy (III) (n=9) | Post therapy (IV) (n=9) | ||||||
Clinical presentation | Cough | 18(85.7%) | 2(9.5%) | 6(66.7%) | 4(44.4%) | <0.001 | 0.232 | 0.028 | 0.343 |
Dyspnea | 20(95.2%) | 1(4.8%) | 6(66.7%) | 5(55.6%) | <0.001 | 0.128 | 0.001 | 0.629 | |
Hemoptysis | 21(100%) | 0 | 9(100%) | 0 | <0.001 | 1.000 | 1.000 | <0.001 | |
Chest pain | 8(38.1%) | 3(14.3%) | 4(44.4%) | 3(33.3%) | 0.079 | 0.745 | 0.232 | 0.629 | |
Respiratory function tests | Mean FVC % | 62.21±1.9 | 66.81±2.8 | 62.11±2.2 | 64.2±3.34 | <0.001 | 0.906 | 0.049 | 0.137 |
Mean FEV1 % | 64.33±3.5 | 71.11±3.8 | 64.69±3.8 | 67.34±3.6 | <0.001 | 0.809 | 0.015 | 0.148 | |
Mean 6MWT (m) | 259±55 | 341±71 | 268±62 | 301±59 | <0.001 | 0.709 | 0.121 | 0.264 | |
Arterial blood gases | Mean PH | 7.382±0.01 | 7.386±0.01 | 7.381±0.02 | 7.383±0.01 | 0.202 | 0.888 | 0.458 | 0.792 |
Mean So2 | 87.11±1.9 | 91.1±1.9 | 86.99±1.6 | 89.1±1.8 | <0.001 | 0.860 | 0.011 | 0.018 | |
Mean PaO2 | 77.12±1.9 | 84.2±2.2 | 76.97±2.1 | 80.4±1.9 | <0.001 | 0.855 | <0.001 | 0.002 | |
Mean PaCo2 | 37.01±1.9 | 42.81±0.9 | 37.72±1.8 | 38.72±1.9 | <0.001 | 0.339 | <0.001 | 0.269 | |
Mean Karnofsky performance score % | 57.30±5.52 | 62.04±6.46 | 57.39±5.76 | 58.28±6.97 | 0.014 | 0.969 | 0.177 | 0.772 | |