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Table 3 Comparison of the clinical presentation outcomes, respiratory function tests, arterial blood gases, and the mean Karnofsky performance score for group A subgroups (main bronchi and lobar bronchi obstruction)

From: The value of endobronchial cryotherapy in the management of malignant endobronchial obstruction in patients with inoperable NSCLC: a prospective analysis of clinical and survival outcomes

Variable Main bronchi (Group A1) Lobar bronchi (Group A2) P values I & II P values I & III P values II & IV P valued III & IV
Pre-cryotherapy
(I)
(n=21)
Post-cryotherapy
(II)
(n=21)
Pre-therapy
(III)
(n=9)
Post therapy
(IV)
(n=9)
Clinical presentation Cough 18(85.7%) 2(9.5%) 6(66.7%) 4(44.4%) <0.001 0.232 0.028 0.343
Dyspnea 20(95.2%) 1(4.8%) 6(66.7%) 5(55.6%) <0.001 0.128 0.001 0.629
Hemoptysis 21(100%) 0 9(100%) 0 <0.001 1.000 1.000 <0.001
Chest pain 8(38.1%) 3(14.3%) 4(44.4%) 3(33.3%) 0.079 0.745 0.232 0.629
Respiratory function tests Mean FVC % 62.21±1.9 66.81±2.8 62.11±2.2 64.2±3.34 <0.001 0.906 0.049 0.137
Mean FEV1 % 64.33±3.5 71.11±3.8 64.69±3.8 67.34±3.6 <0.001 0.809 0.015 0.148
Mean 6MWT (m) 259±55 341±71 268±62 301±59 <0.001 0.709 0.121 0.264
Arterial blood gases Mean PH 7.382±0.01 7.386±0.01 7.381±0.02 7.383±0.01 0.202 0.888 0.458 0.792
Mean So2 87.11±1.9 91.1±1.9 86.99±1.6 89.1±1.8 <0.001 0.860 0.011 0.018
Mean PaO2 77.12±1.9 84.2±2.2 76.97±2.1 80.4±1.9 <0.001 0.855 <0.001 0.002
Mean PaCo2 37.01±1.9 42.81±0.9 37.72±1.8 38.72±1.9 <0.001 0.339 <0.001 0.269
Mean Karnofsky performance score % 57.30±5.52 62.04±6.46 57.39±5.76 58.28±6.97 0.014 0.969 0.177 0.772