|
Factors
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
OR (95% CI)
|
p value
|
OR (95% CI)
|
p value
|
|---|
|
Age (≥ 55 years)
|
3.4 (2.2–5.3)
|
< 0.001^
|
0.87 (0.420–1.8)
|
0.709
|
|
Sex (Ref. = female)
|
|
Male
|
1.6 (1.0–2.4)
|
0.042^
|
1.8 (0.94–3.5)
|
0.075
|
|
Fever
|
2.9 (1.7–5.0)
|
< 0.001^
|
1.1 (0.49–2.6)
|
0.774
|
|
Constitutional symptoms
|
2.1 (1.4–3.3)
|
0.001
|
1.3 (0.69–2.6)
|
0.390
|
|
Cough
|
2.5 (1.5–4.1)
|
< 0.001^
|
1.0 (0.48–2.2)
|
0.971
|
|
Dyspnea
|
4.8 (3.0–7.6)
|
< 0.001^
|
2.3 (1.1–5.0)
|
0.032^
|
|
Presence of comorbidity
|
3.0 (1.9–4.8)
|
0.001^
|
3.0 (1.4–6.3)
|
0.004^
|
|
Anemic (HB < 12 g/dl)
|
3.2 (2.1–5.1)
|
< 0.001^
|
3.4 (1.7–6.5)
|
< 0.001 ^
|
|
WBCs (Ref. = 4–10*103/ul)
|
|
Low (< 4)
|
0.72 (0.34–1.5)
|
0.394
|
1.4 (0.45–4.6)
|
0.541
|
|
High (> 10)
|
3.0 (1.9–4.8)
|
< 0.001
|
1.03 (0.48–2.2)
|
0.934
|
|
High neutrophil (> 7*103/ul)
|
3.6 (2.3–5.6)
|
< 0.001^
|
1.2 (0.40–3.6)
|
0.760
|
|
Low lymphocyte % (< 20)
|
4.1 (2.5–6.7)
|
< 0.001^
|
0.63 (0.26–1.5)
|
0.303
|
|
Low absolute lymphocytes (< 1.5*103/ul)
|
2.9 (1.8–4.8)
|
< 0.001^
|
0.61 (0.24–1.6)
|
0.327
|
|
High NLR (> 8)
|
9.7 (5.8–16.2)
|
< 0.001^
|
7.2 (2.9–17.7)
|
< 0.001 ^
|
|
High PLR (> 192)
|
4.3 (2.7–6.9)
|
< 0.001^
|
3.2 (1.4–7.7)
|
0.008 ^
|
|
INR (≥ 1.1)
|
3.1 (1.8–5.1)
|
< 0.001^
|
1.8 (0.86–3.9)
|
0.119
|
|
Low albumin (< 34 g/L)
|
1.6 (1.0–2.5)
|
0.037^
|
0.922 (0.49–1.8)
|
0.806
|
|
High AST (> 34 U/L)
|
1.8 (1.2–2.8)
|
0.006^
|
1.3 (0.64–2.5)
|
0.496
|
|
High ALT (> 45 U/L)
|
2.2 (1.4–3.4)
|
0.001^
|
1.9 (0.93–4.0)
|
0.079
|
|
High BUN (> 8.2 mmol/L)
|
3.4 (2.1–5.3)
|
< 0.001^
|
1.6 (0.86–3.1)
|
0.135
|
|
High ferritin (> 440 ng/ml)
|
4.9 (3.1–7.7)
|
< 0.001^
|
1.5 (0.77–3.0)
|
0.226
|
|
High D-dimer (> 0.9 mg/L)
|
5.8 (3.6–9.2)
|
< 0.001^
|
2.3 (1.2–4.3)
|
0.011 ^
|
|
High CRP (> 23 mg/dl)
|
3.7 (2.3–5.9)
|
< 0.001^
|
1.3 (0.62–2.)
|
0.519
|
- HB hemoglobin, WBCs white blood cells, NLR neutrophil lymphocytic ratio, PLR platelets lymphocytic ratio, INR international normalization ratio, AST aspartate aminotransferase, ALT alanine aminotransferase, BUN blood urea nitrogen, CRP C-reactive protein
- ^Significant p value
