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Table 4 Univariate Cox analysis of COVID-19 risk factors for mortality

From: Predictors of severity and mortality in COVID-19 patients

Demographic character

Improved (n = 141)

Died (n = 34)

P

Age

57.085 ± 13.3

66.265 ± 15.18

0.002ƪ

Sex

 Femalea

34 (24.1%)

5 (14.7%)

0.21$

 Malea

107 (75.9%)

29 (85.3%)

 

Comorbiditya

71 (50.35%)

25 (73.5%)

0.02$

 DMa

50 (35.46%)

13 (38.2%)

0.84$

 HTNa

46 (32.62%)

17 (50%)

0.05$

 IHDa

5 (3.55%)

3 (8.8%)

0.18$

 Malignancya

4 (2.84%)

3 (8.8%)

0.13$

 Renal diseasea

5 (3.55%)

8 (23.5%)

< 0.001$

 Respiratory co-infection

6 (4.26%)

13 (38.24%)

< 0.001$

Severe/criticala

37 (26.2%)

30 (88.2%)

< 0.001$

Oxygen usea

76 (53.9%)

34 (100%)

< 0.001$

 Standard oxygena

74 (52.48%)

17 (50%)

0.84$

 HFNCa

22 (15.6%)

10 (29.4%)

0.06$

 NIVa

7 (4.9%)

8 (23.5%)

0.001$

 IMVa

4 (2.8%)

32 (94.12%)

< 0.001$

Admission labs

 TLC (× 103/μl)b

10 (6.9–13)

17.9 (13.1–24.2)

< 0.001§

 Lymphocyte (/μl)b

1650 (1218–2267)

1093 (765–1476)

< 0.001§

 HB (g/dl)c

13.34 ± 1.88

12.547 ± 2.054

0.03ƪ

 PLT (× 103/μl)b

319 (235.5–407)

272.5 (187.5–347.5)

0.009§

 AST (U/l)b

39 (28–57.5)

74.5 (49.2–133.2)

< 0.001§

 ALT (U/l)b

50 (32–78.5)

70.5 (39.7–168.2)

0.01§

 Urea (mg/dl)b

47 (39–67)

156.5 (93.2–212.2)

< 0.001§

 Creatine (mg/dl)b

1 (0.9–1.3)

1.5 (0.8–3.4)

0.008§

 d-dimer (μg/ml)b

711.21 (459.7–1396)

5907.4 (2414.7–8497.1)

< 0.001§

 Ferritin (ng/ml)b

890 (457.5–1555.5)

2593.5 (1361.7–3913.7)

< 0.001§

 CRP (mg/l)b

87.7 (34.2–157.9)

223.7 (84.7–290.3)

< 0.001§

  1. DM Diabetes mellitus, HTN Hypertension, IHD Ischemic heart disease, HFNC High-flow nasal cannula, NIV Noninvasive ventilation, IMV Invasive mechanical ventilation, TLC Total leukocytic count, Hb Hemoglobin, PLT Platelets, AST Aspartate aminotransferase, ALT Alanine transaminase, CRP C-reactive protein
  2. ƪIndependent t-test
  3. §Mann-Whitney test
  4. $Chi-square test, P < 0.05 considered significant
  5. aData are represented as number and percentage
  6. bData are represented as median and interquartile range
  7. cData are represented as mean and standard deviation