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Table 7 Predictors of severe acute exacerbation among enrolled patients

From: Acute severe asthma in emergency department: clinical characteristics, risk factors, and predictors for poor outcome

Predictors

Odds ratio

95% confidence interval

P-value

Age (>40 years)

2.11

1.89–3.45

<0.001*

Previous MV

1.20

1.10–3.01

<0.001*

OSA

1.11

1.01–2.35

<0.001*

Overuse of SABA

2.01

1.87–4.02

<0.001*

Uncontrolled asthma

3.33

2.50–5.05

<0.001*

Depression (moderate and severe)

2.30

1.78–4.35

<0.001*

Eosinophilia (> 300 cells/μl)

1.45

1.20–2.59

<0.001*

SO2 <90%

4.56

3.45–7.56

<0.001*

PEFR (after1-h treatment)

3.34

1.90–4.9

<0.001*

  1. MV, mechanical ventilation; OSA, obstructive sleep apnea; SABA, short-acting β agonist; depression assessed using Beck Depression Inventory 2 (BDI-II); SO2, oxygen saturation; PEFR, peak expiratory flow rate