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The Egyptian Journal of Bronchology

Table 2 Tissue expression of PDL-1, VDR with serum vit. D level for studied markers in control and different pathological types of lung cancer

From: Gene expression of programmed cell death ligand-1 (PDL-1) and vitamin D receptor (VDR) with the serum vitamin D3 in lung cancer

 

PDL-1 expression

VDR

expression

Vitamin D

serum (ng/ml)

Controls

0.98 ± 0.04

1.06 ± 0.06

33.28 ± 2.51

Adenocarcinoma

n = 17

4.97 ± 0.85 a***

0.43 ± 0.05a***

23.76 ± 3.09

Squamous cell carcinoma n = 14

6.84 ± 1.33 a***

0.41 ± 0.05a***

32.76 ± 2.76

Large cell carcinoma n = 12

2.18 ± 0.19

0.59 ± 0.06a***

17.85 ± 3.23 a**

Small cell carcinoma

n = 11

6.41 ± 1.45 a***

0.39 ± 0.05a***

21.16 ± 2.36 a*

Stage I of LC

n = 24

3.41 ± 0.66 a**

0.46 ± 0.04 a***

25.66 ± 2.75

Stage II of LC

n = 30

6.56 ± 0.0.79 a***, e***

0.43 ± 0.04 a***

22.29 ± 2.42 a*

  1. PDL-1 programmed death ligand-1, VDR vitamin D receptor
  2. The analysis was run using one-way ANOVA test followed by Tukey’s multiple comparison test. aCompared to control group
  3. eCompared to stage I group, *P < 0.05, **P < 0.01, ***P < 0.001 (data are represented as means ± SE)
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