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Table 7 Validity of TLC, ALC, CRP, ferritin, LDH, and D-dimer for discrimination between negative and positive CT

From: CO-RADS score and its correlation with clinical and laboratory parameters in patients with COVID-19

 

WBCs

ALC

CRP

Ferritin

LDH

D-dimer

AUC

0.625

0.927

0.900

0.931

0.940

0.801

95% CI

0.487–0.764

0.869–0.985

0.818–0.981

0.834–1

0.878–1

0.715–0.887

Cut off

7.9

1.4

5.5

135

151

0.31

Sensitivity (%)

54.5

88.6

83

94.3

93.2

63.6

Specificity (%)

75

91.7

91.7

91.7

83.3

91.7

PPV (%)

54.5

88.6

83.0

94.3

93.2

63.6

NPV (%)

75.0

91.7

91.7

91.7

83.3

91.7

Accuracy (%)

57.0

89.0

84.0

94.0

92.0

67.0

  1. WBCs White blood cells (4000–10000/mm3), ALC Absolute lymphocyte count (1000–4800/mm3), CRP C-reactive protein (0–5 mg/L), LDH Lactate dehydrogenase (135–225 U/L), AUC Area under the curve, CI confidence interval, PPV Positive predictive value, NPP Negative predictive value