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Table 2 Resting arterial blood gases and RHC-derived data

From: Physiological predictors of resting pulmonary hypertension associated with COPD: a retrospective analysis

Variable

All patients (n = 69)

COPD-PH (n = 33)

COPD-non-PH (n = 36)

P value

Resting arterial blood gases breathing ambient room air

 pH

7.38 ± 0.03

7.37 ± 0.04

7.38 ± 0.03

0.34

 PaO2, mmHg

62.4 ± 10.6

59.6 ± 10.0*

65.0 ± 10.6

0.03

 PaCO2, mmHg

49.7 ± 6.0

50.8 ± 6.1

48.8 ± 5.8

0.19

 HCO3

29.7 ± 3.9

30.6 ± 4.4

28.8 ± 3.1

0.06

 SaO2, %

90 ± 5

90 ± 5

91 ± 4

0.24

Selected RHC measurements, median (IQR)

 Systolic PAP, mmHg

34.0 (28.8–40.0)

40.0 (37.0–45.0) *

29.0 (24.5–33.0)

 < 0.001

 Diastolic PAP, mmHg

17.0 (13.8–21.0)

21.0 (19.8–24.0) *

14.0 (11.0–16.0)

 < 0.001

 Mean PAP, mmHg

22.0 (19.3–27.3)

27.3 (25.6–29.4) *

19.5 (16.7–21.0)

 < 0.001

 PAWP, mmHg

6.0 (4.0–8.0)

7.0 (4.0–9.3)

6.0 (4.5–7.0)

0.12

 CO, L/min

5.25 (4.75–5.96)

5.07 (4.56–5.96)

5.46 (4.89–5.97)

0.30

 CI, L/min/m2

3.10 (2.68–3.45)

2.99 (2.56–3.35)

3.10 (2.75–3.63)

0.52

 PVR, WU

2.94 (2.32–4.32)

4.31 (3.53–5.36) *

2.39 (1.77–3.84)

 < 0.001

  1. Values are means ± SD unless otherwise specified. *P < 0.05 COPD-PH patients vs. COPD-non-PH
  2. CI Cardiac index, CO Cardiac output, COPD Chronic obstructive pulmonary disease, HCO3 bicarbonate, IQR Interquartile range, PaCO2 Partial pressure of arterial carbon dioxide, PaO2 Partial pressure of arterial oxygen, PAP Pulmonary artery pressure, PAWP Pulmonary artery wedge pressure, PH Pulmonary hypertension, PVR Pulmonary vascular resistance, RHC Right heart catheterization, SaO2 arterial hemoglobin oxygen saturation, WU wood units