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Table 2 Comparison of various parameters among success and failure group

From: NIV failure in respiratory failure: an analysis

 

Success

(n = 77)

Failure (n = 19)

p-value

Mean ± 

standard deviation

Mean ± 

standard deviation

Age (years)

67.9 ± 9.3

65.8 ± 

15.0

0.446

BMI (kg/m2)

26.0 ± 5.0

24.3 ± 

5.2

0.195

Initial heart rate (per minute)

102.5 ± 

17.9

116.3 ± 

20.0

0.004

Initial respiratory rate (per minute)

28.0 ± 

6.4

34.3 ± 

8.5

p < 0.01

GCS score

14.8 ± 

0.6

14.5 ± 

0.9

0.058

Initial SpO2 (%)

81.0 ± 

13.1

74.3 ± 

17.2

0.062

Initial pH

7.3 ± 

0.1

7.3 ± 

0.1

0.032

pH at 1–2 h

7.3 ± 

0.1

7.2 ± 

0.1

p < 0.01

pH at 4–6 h*

7.3 ± 

0.1

7.2 ± 

0.1

p < 0.01

pCO2 — initial (mm Hg)

67.1 ± 

19.4

69.4 ± 

22.8

0.655

pCO2 at 1–2 h (mm Hg)

64.1 ± 

17.3

76.9 ± 25.7

0.011

pCO2 at 4–6 h* (mm Hg)

60.0 ± 

16.6

74.4 ± 33.1

0.012

PaO2 initial (mm Hg)

85.3 ± 

47.7

65.8 ± 

22.8

0.088

Bicarbonate level (mEq/L)

29.5 ± 

6.7

27.6 ± 

6.3

0.276

Sodium (mEq/L)

135.9 ± 

5.7

129.2 ± 

8.8

p < 0.01

CRP (mg/L)

34.6 ± 

46.7

61.6 ± 

80.1

0.057

APACHE II score

14.1 ± 

4.3

19.2 ± 

4.4

p < 0.01

Charlson index

5.0 ± 

1.7

6.7 ± 2.1

p < 0.01

SAPS II score

22.0 ± 

4.8

27.6 ± 5.6

p < 0.01

  1. BMI Body mass index, GCS Glasgow Coma Scale, CRP C-reactive protein, APACHE Acute Physiology and Chronic Health Evaluation, SAPS Simplified acute physiology score