Table 3 Health-related quality of life (HRQoL) and mental health

Weight change, %

 − 0.5 (− 5.6, + 0.29)

0.0 (− 4.8, + 1.5)

 − 2.6 (− 9.5, 0.0)

–

–

0.317

SF-36 domains

    Physical functioning

75.0 (60.0, 90.0)

75.0 (57.5, 90.0)

75.0 (60, 90)

87.5 (78.7, 96.3)

0.028

0.532

    Role limitations due to physical health

87.5 (25.0, 100)

75.0 (25.0, 100)

100 (0.0, 100)

100 (100, 100)

0.013

0.706

    Role limitations due to emotional health

66.7 (0.0, 100)

33.0 (0.0, 100)

100 (33.0, 100)

100 (66.7, 100)

0.013

0.063

    Energy

55.0 (36.3, 65.0)

50.0 (37.5, 65.0)

60.0 (35.0, 70.0)

62.5 (60.0, 75.0)

0.018

0.385

    Emotional well-being

60.0 (45.0, 76.0)

56.0 (42.0, 68.0)

72.0 (52.0, 80.0)

68.0 (61.5, 72.0)

0.185

0.118

    Social functioning

62.5 (37.5, 75.0)

50.0 (37.5, 75.0)

62.5 (50.0, 87.5)

75.0 (59.4, 87.5)

0.051

0.177

    Pain

67.5 (55.6, 77.5)

67.5 (50.0, 77.5)

67.5 (57.5, 87.5)

90.0 (75.0, 100)

0.002

0.589

    General health

55.0 (35.0, 73.8)

55.0 (35.0, 70.0)

60.0 (45.0, 80.0)

70.0 (65.0, 80.0)

0.014

0.429

    Brief Fatigue Inventory (BFI)

4.78 (2.72, 6.56)

5.11 (2.89, 6.56)

3.78 (2.11, 6.22)

2.67 (1.89, 3.11)

0.004

0.258

    BFI score ≥ 7

14.0% (7)

20.0%(7)

0.0% (0)

0.0% (0)

0.328

0.087

    Hamilton Anxiety Scale (HAM-A)

13.0 (7.5, 20.5)

13.0 (9.0, 22.0)

11.0 (6.0, 17.0)

4.0 (2.3, 7.8)

 < 0.001

0.386

    HAM-A score 25 to 30

20% (10)

20% (7)

20% (3)

0.0% (0)

0.188

1.00

    Post-traumatic stress disorder Checklist (PCL)

39.0 (28.0, 51.3)

44.0 (29.0, 52.0)

29.0 (20.0, 45.0)

–

–

0.039

    PCL score > 33

58.0%(29)

71.4% (25)

27% (4)

–

–

0.004