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Table 5 Echocardiographic and electrocardiographic findings

From: Midterm follow-up of healthy young adults with moderate to severe COVID-19: pulmonary and extrapulmonary disease sequelae

Cases, median (IQR)/% (N)

Control

Median (IQR)/% (N)

PV1

PV 2

All

Non-ICU

ICU

110 (110, 120)

110 (105, 120)

110 (110, 126)

115 (102, 120)

0.978

0.647

70 (70, 80)

70 (70, 80)

70 (67, 70)

75 (62, 93)

0.579

0.349

78 (70 – 81)

76 (68, 80)

80 (76, 82)

84 (79, 91)

0.029

0.035

Electrocardiographic measures

 ECG rhythm

  86%(43)

83% (29)

93% (14)

1.000

  6% (3)

6% (2)

7% (1)

  4% (2)

6% (2)

0% (0)

  4% (2)

6% (2)

0% (0)

  14% (7)

11% (4)

20% (3)

0.415

  8% (4)

9% (3)

7% (1)

1.000

  34% (17)

34% (12)

33% (5)

0.948

  36% (18)

40% (14)

27% (4)

0.368

  32% (16)

29% (10)

40% (6)

0.427

  30% (15)

37% (13)

13% (2)

0.092

  20% (10)

20% (7)

20% (3)

1.000

  8% (4)

9% (3)

7% (1)

1.000

  28% (14)

29% (0)

27% (4)

0.891

  407 (385, 424)

402 (351, 426)

413 (392, 423)

0.396

  8% (4)

6% (2)

13% (2)

0.574

 Echocardiography

  6% (3)

0% (0)

21% (3)

0% (0)

1.000

0.022

  30% (14)

18% (6)

57% (7)

17% (2)

0.482

0.008

  4.33 (4.00, 4.55)

4.36 (4.00, 4.56)

4.17 (3.74, 4.61)

4.53 (4.40, 4.80)

0.019

0.496

  2.1 (2.1, 2.3)

2.1 (2.1, 2.25)

2.1 (1.8, 2.4)

2.4 (2.4, 2.8)

 < 0.001

0.563

  − 18.2 (− 19.6, − 17.1)

 − 18.7 (− 20.4, − 17.3)

 − 17.3 (− 18.9, − 14.8)

 − 19.0 (− 19.6, − 18.0)

0.347

0.026

  46% (21)

38% (12)

64% (9)

27% (3)

0.267

0.093

  20% (9)

9% (3)

43% (6)

9% (1)

0.412

0.015

  7.9 (6.2, 9.4)

8.0 (7.0, 9.8)

6.0 (4.8, 9.1)

9.4 (8.0, 11.2)

0.049

0.026

  12.0 (9.8, 14.0)

12.5 (10.2, 14.5)

11.3 (7.8, 13.3)s

12.0 (10.5, 15.0)

0.820

0.098

  2.92 (2.80, 3.20)

2.80 (2.80, 3.10)

3.13 (2,85, 3.27)

2.77 (2.68, 2.98)

0.062

0.077

  10.0 (9.0, 11.8)

10.0 (9.1, 11.2)

10.2 (8.5, 12.1)

10.0 (9.3, 11.6)

0.878

0.930

  0.0% (0)

0.0% (0)

0.0% (0)

0.0% (0)

  21.0 (19.0, 23.0)

21.0 (20.0, 22.8)

20.0 (18.0, 23.5)

22.5 (21.0, 24.0)

0.081

0.454

  24% (11)

19% (6)

39% (5)

10% (1)

0.317

0.163

  − 18.6 (− 21.8, − 14.9)

 − 19.1 (− 22.0, − 15.1)

 − 17.4 (− 21.1, − 11.5)

 − 20.0 (− 22.6, − 16.0)

0.117

0.093

  20.0 (20.0, 22.3)

20.0 (20.0, 23.0)

20.0 (20.0, 22.0)

21.0 (21.0, 22.5)

0.124

0.400

  2% (1)

3% (1)

0.0% (0)s

0.0% (0)

1.00

1.00

  0.0% (0)

0.0% (0)

0.0% (0)

0.0% (0)

  1. Values are in median and interquartile range, or n (%) E/e' early mitral inflow velocity/mitral annular early diastolic velocity, EF ejection fraction, IQR interquartile range, LV left ventricular, LVEDd left ventricular end-diastolic dimension, LVESd left ventricular end-systolic dimension, LVEF left ventricular ejection fraction, LVOT left ventricular outflow tract, RV right ventricular, RV S' right ventricular systolic excursion velocity, TAPSE tricuspid annular plane systolic excursion
  2. RVLS right ventricular longitudinal strain, PASP pulmonary artery systolic pressure, TR tricuspid regurgitation
  3. Visually estimated impaired right ventricular function, n (%)
  4. QTc is prolonged if > 440 ms in men or > 460 ms in women
  5. All boldface entries are significant in this version