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Table 1 Comparison between the different degrees of severity of COVID-19 infection and the demographic characteristics and outcomes

From: Correlation between the serum level of ferritin and D-dimer and the severity of COVID-19 infection

 

All patients

Mild

Moderate

Severe

Critical

Test value

P value

No. = 150

No. = 39

No. = 21

No. = 18

No. = 72

Age (years)

Mean ± SD

54.50 ± 18.44

38.13 ± 13.45

49.33 ± 18.08

53.78 ± 16.39

65.06 ± 13.87

29.300 b

 < 0.0001

Range

10–87

17–71

10–72

28–82

26–87

Sex

Female

72

24 (61.5%)

8 (38.1%)

7 (38.9%)

33 (45.8%)

4.423a

0.219

Male

78

15 (38.5%)

13 (61.9%)

11 (61.1%)

39 (54.2%)

Smoking status

Non-smoker

 

37 (94.9%)

17 (81.0%)

14 (77.8%)

54 (75.0%)

8.307a

0.216

Current smoker

122(81.3%)

16 (10.7%)

12 (8.0%)

2 (5.1%)

3 (14.3%)

2 (11.1%)

9 (12.5%)

Ex-smoker

 

0 (0.0%)

1 (4.8%)

2 (11.1%)

9 (12.5%)

Comorbidities

Yes

54 (36%)

3 (7.7%)

5 (23.8%)

8 (44.4%)

38 (52.8%)

24.272a

 < 0.0001

 

Diabetes

30 (20.0%)

2 (5.1%)

1 (4.8%)

3 (16.7%)

24 (33.3%)

16.564a

0.001

 

Hypertension

33 (22.0%)

2 (5.1%)

2 (9.5%)

5 (27.8%)

24 (33.3%)

14.114a

0.003

 

IHD

11 (7.3%)

1 (2.6%)

0 (0.0%)

2 (11.1%)

8 (11.1%)

4.857a

0.183

 

CKD

14 (9.3%)

1 (2.6%)

2 (9.5%)

2 (11.1%)

9 (12.5%)

3.033a

0.387

 

CLD

7 (4.7%)

0 (0.0%)

0 (0.0%)

1 (5.6%)

6 (8.3%)

5.145a

0.161

 

AF

4 (2.7%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

4 (5.6%)

4.452a

0.217

 

Heart failure

2 (1.3%)

1 (2.6%)

0 (0.0%)

0 (0.0%)

1 (1.4%)

0.978a

0.807

ICH

2 (1.3%)

0 (0.0%)

0 (0.0%)

1 (5.6%)

1 (1.4%)

3.252a

0.354

Acute kidney injury

2 (1.3%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

2 (2.8%)

2.196a

0.533

 

Neurological disorders

10 (6.6%)

0 (0.0%)

1 (4.8%)

1 (5.6%)

9 (12.5%)

6.203a

0.102

Primary outcome (mortality)

Survivor

96 (64.0%)

39 (100.0%)

21 (100.0%)

18 (100.0%)

18 (25.0%)

91.406 a

 < 0.0001

Non-Survivor

54 (36.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

54 (75.0%)

Days of hospital stay

Range

1–32

8 (4–13)

8 (7–12)

10 (8–16)

8.5 (6–13.5)

4.508 c

0.212

2–30

4–20

3–26

1–32

Need for ICU

admission

Yes

75 (50.0%)

1 (2.6%)

0 (0.0%)

5 (27.8%)

69 (95.8%)

120.158 a

 < 0.0001

Need for mechanical ventilation

Yes

55 (36.7%)

0 (0.0%)

0 (0.0%)

1 (5.6%)

54 (75.0%)

87.799 a

 < 0.0001

  1. P value > 0.05 non-significant, P value < 0.05 significant, P value < 0.01 highly significant
  2. aChi-square test
  3. bOne-way ANOVA test
  4. cKruskal-Wallis test, IHD Ischemic heart disease, CKD Chronic kidney disease, CLD Chronic liver disease, AF Atrial fibrillation, ICH Intra-cranial haemorrhage, IQR Inter-quartile range