Correlation between serum uric acid and pulmonary arterial hypertension based on echo probability in patients with obstructive sleep apnea syndrome

Sweed, Rania Ahmad; Bedair, Ghadeer Mostafa Mohamed; Shaban, Ahmed Yousef; Shaarwy, Hany Amin

doi:10.1186/s43168-023-00219-0

The Egyptian Journal of Bronchology

Table 1 Polysomnographic data of different severity groups (n = 100)

From: Correlation between serum uric acid and pulmonary arterial hypertension based on echo probability in patients with obstructive sleep apnea syndrome

	Total (n = 100)	OSAHS severity			Test of sig	p
	Total (n = 100)	Mild (n = 6)	Moderate (n = 38)	Severe (n = 56)	Test of sig	p
AHI
Min.–max	7.70–55.0	7.70–11.30	16.80–29.60	30.0–55.0	F = 143.58^*	< 0.001^*
Mean ± SD	31.93 ± 11.78	9.0 ± 1.79	22.98 ± 4.19	40.45 ± 7.14
Median (IQR)	32.0 (22.0–39.0)	8.0 (7.70–11.30)	22.0 (18.90–26.70)	38.25 (35.0–47.50)
Sig. bet. categ		p₁ < 0.001^, p₂ < 0.001^, p₃ < 0.001^*
RDI
Min.–max	7.70–55.0	7.70–11.30	16.80–55.0	15.30–55.0	F = 57.284^*	< 0.001^*
Mean ± SD	32.66 ± 12.26	9.87 ± 1.71	25.50 ± 8.63	39.97 ± 8.58
Median (IQR)	33.0 (22.20–41.0)	10.60 (7.70–11.30)	23.20 (20.0–29.10)	39.35 (35.0–48.35)
Sig. bet. categ		p₁ < 0.001^, p₂ < 0.001^, p₃ < 0.001^*
t90%
Min.–max	0.0–38.0	0.0–0.0	0.0–38.0	0.10–38.0	H = 43.917^*	< 0.001^*
Mean ± SD	7.17 ± 8.90	0.0 ± 0.0	3.96 ± 8.56	10.12 ± 8.47
Median (IQR)	5.30 (0.90–9.80)	0.0 ( −)	1.20 (0.40–3.50)	7.65 (5.85–11.85)
Sig. bet. categ		p₁ = 0.033^, p₂ < 0.001^, p₃ < 0.001^*
ODI
Min.–max	1.70–60.0	1.70–9.30	7.80–60.0	15.0–60.0	H = 44.825^*	< 0.001^*
Mean ± SD	22.21 ± 13.89	4.57 ± 3.69	18.44 ± 10.75	26.65 ± 14.29
Median (IQR)	18.60 (16.10–20.8)	2.70 (1.70–9.30)	16.1 (15.20–16.90)	19.7 (18.65–26.20)
Sig. bet. categ		p₁ = 0.023^, p₂ < 0.001^, p₃ < 0.001^*
Minimal SpO₂%
Min.–max	30.0–92.0	91.0–92.0	30.0 – 90.0	30.0–89.0	F = 36.977^*	< 0.001^*
Mean ± SD	57.48 ± 18.98	91.67 ± 0.52	66.47 ± 15.25	47.71 ± 14.54
Median (IQR)	52.50 (41.0–70.0)	92.0 (91.0–92.0)	64.0 (58.0–85.0)	45.0 (38.0–51.0)
Sig. bet. categ		p₁ < 0.001^, p₂ < 0.001^, p₃ < 0.001^*
Baseline O₂ sat
Min.–max	90.0–99.0	95.0–97.0	90.0–99.0	91.0–97.0	F = 5.240^*	0.007^*
Mean ± SD	93.94 ± 1.90	96.0 ± 0.89	94.16 ± 2.21	93.57 ± 1.58
Median (IQR)	94.0 (92.0–95.0)	96.0 (95.0–97.0)	94.0 (92.0–96.0)	93.0 (92.0–95.0)
Sig. bet. categ		p₁ = 0.061, p₂ = 0.007^*, p₃ = 0.282

IQR Interquartile range, SD Standard deviation, F F For ANOVA test, pairwise comparison bet. Each 2 groups was done using post hoc test (Tukey). H H for Kruskal–Wallis test, pairwise comparison bet. Each 2 groups was done using post hoc test (Dunn’s for multiple comparisons test). p p-value for comparing between different categories. p₁ p-value for comparing between mild and moderate. p₂ p-value for comparing between mild and severe. p₃ p-value for comparing between moderate and severe
^*Statistically significant at p ≤ 0.05

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