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Table 1 Demographic and clinical characteristics of the study population (n = 50)

From: Clinical, physiological, and radiological different phenotypes of COPD patients

 

Patients with COPD with CT scan data (n = 50)

P value

Mild CLE

(n = 29)

Moderate CLE (n = 8)

CON

(n = 5)

ADE

(n = 5)

PSE

(n = 3)

Age (years), (mean ± SD)

61.79 ± 15.19

68.25 ± 10.91

64.00 ± 8.97

61.40 ± 11.90

50.67 ± 5.50

0.431¥

Gender, n (%)

 

0.533*

 Male

25 (54.3)

8 (17.4)

5 (10.9)

5 (10.9)

3 (6.5)

 Female

4 (100.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Body mass index (kg/m.2) (mean ± SD)

28.14 ± 5.51

25.63 ± 5.96

26.63 ± 5.33

28.58 ± 8.03

26.20 ± 4.32

0.804¥

Smoking status, n (%)

 

0.501*

 Non-smoker

4 (100.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Ex-smoker

8 (66.7)

3 (25.0)

0 (0.0)

1 (8.3)

0 (0.0)

 Current smoker

17 (50.0)

5 (14.7)

5 (14.7)

4 (11.8)

3 (8.8)

Smoking index, mean ± SD

424.04 ± 138.2

484.38 ± 108.0

386.60 ± 72.5

548.20 ± 143.4

233.33 ± 49.3

0.046¥

Biomass fuel exposure, N (%)

 

0.428*

 

7 (70.0)

1 (10.0)

2 (20.0)

0 (0.0)

0 (0.0)

Need for hospitalization last year, n (%)

 

 < 0.001*

 

3 (17.6)

3 (17.6)

5 (29.4)

4 (23.5)

2 (11.8)

Associated comorbidities, n (%)

 DM

5 (55.6)

3 (33.3)

0 (0.0)

1 (11.1)

0 (0.0)

0.428*

 HTN

4 (36.4)

3 (27.3)

1 (9.1)

3 (27.3)

0 (0.0)

0.120

 Cardiac

3 (50.0)

2 (33.3)

0 (0.0)

1 (16.7)

0 (0.0)

0.601

 Renal

1 (50.0)

0 (0.0)

0 (0.0)

1 (50.0)

0 (0.0)

0.403

 Liver

4 (57.1)

1 (14.3)

1 (14.3)

1 (14.3)

0 (0.0)

0.938

 History of asthma

2 (66.7)

0 (0.0)

0 (0.0)

1(33.3)

0 (0.0)

0.592

Chest symptoms, n (%)

 Cough

29 (58.0)

8 (16.0)

5 (10.0)

5 (10.0)

3 (6.0)

0.123*

 Sputum

28 (57.1)

8 (16.3)

5 (10.2)

5 (10.2)

3 (6.1)

0.440

 Dyspnea

29 (58.0)

8 (16.0)

5 (10.0)

5 (10.0)

3 (6.0)

0.420

 Wheezes

19 (65.5)

6 (20.7)

2 (6.9)

1 (3.4)

1 (3.4)

0.602

 Chest pain

2 (33.3)

2 (33.3)

0 (0.0)

1 (16.7)

1 (16.7)

0.403

 Hemoptysis

1 (50.0)

0 (0.0)

0 (0.0)

0 (0.0)

1 (50.0)

0.422

  1. CLE centrilobular emphysema, ADE advanced destructive emphysema, Con confluent emphysema, PSE paraseptal emphysema
  2. *Pearson Monte Carlo test; ¥ANOVA test