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Table 5 Pulmonary function test parameters of the study population stratified according to CT diverse phenotype groups (n = 50)

From: Clinical, physiological, and radiological different phenotypes of COPD patients

 

Patients with COPD with CT scan data (n = 50), mean ± SD

P value¥

Mild CLE

(n = 29)

Moderate CLE (n = 8)

CON

(n = 5)

ADE

(n = 5)

PSE

(n = 3)

Pre-bronchodilator (%)

 FEV1

58.00 ± 5.02

61.25 ± 2.05

51.40 ± 5.89

50.80 ± 3.63

57.33 ± 2.88

 < 0.001

 FVC

94.07 ± 3.55

92.25 ± 3.95

93.60 ± 2.07

91.00 ± 5.14

95.00 ± 1.73

0.351

 FEV1/FVC

54.14 ± 3.94

53.25 ± 4.49

55.00 ± 3.31

54.20 ± 3.83

54.67 ± 3.05

0.950

Post-bronchodilator (%)

 FEV1

59.62 ± 4.36

60.38 ± 5.06

58.00 ± 5.70

65.00 ± 1.22

63.33 ± 3.21

0.043

 FVC

94.97 ± 3.09

93.75 ± 3.32

94.40 ± 1.67

92.20 ± 4.55

95.00 ± 1.73

0.442

 FEV1/FVC

57.17 ± 4.08

55.88 ± 4.48

57.60 ± 3.36

56.60 ± 4.72

57.00 ± 2.64

0.938

  1. Row percent was used ¥ ANOVA test
  2. FEV1 forced expiratory volume in one second, FVC forced vital capacity, CLE centrilobular emphysema, ADE advanced destructive emphysema, CON Confluent emphysema, PSE Paraseptal emphysema