Incidence of thrombophilic gene polymorphism (MTHFR C677T) in Egyptian COVID-19 patients and its clinical implications

The Egyptian Journal of Bronchology

Table 4 Comparison between the study and control groups as regards age, sex, and MTHFR gene mutation

		Control group	Patients group	Test value	P-value	Sig
		No. = 13	No. = 33	Test value	P-value	Sig
Age [n (%)]	Mean ± SD	34.85 ± 13.13	45.42 ± 10.56	− 2.853^b	0.007	HS
Age [n (%)]	Range	20–64	25–67	− 2.853^b	0.007	HS
Sex [n (%)]	Female	7 (53.8%)	14 (42.4%)	0.490^a	0.484	NS
Sex [n (%)]	Male	6 (46.2%)	19 (57.6%)	0.490^a	0.484	NS
MTHFR gene mutation [n (%)]	Absent	8 (61.5%)	23 (69.7%)	0.870^a	0.647	NS
	Heterozygous	5 (38.5%)	9 (27.3%)
	Homozygous	0 (0.0%)	1 (3.0%)

P value > 0.05 non-significant (NS); P value < 0.05 significant (S); P value < 0.01 highly significant (HS)
^aChi-square test
^bIndependent t-test, IQR interquartile range