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Table 6 Laboratory data in the study group according to mutation of the MTHFR gene

From: Incidence of thrombophilic gene polymorphism (MTHFR C677T) in Egyptian COVID-19 patients and its clinical implications

 

MTHFR gene mutation

Test value

P value

Sig

Absent

Present

No. = 23

No. = 10

Laboratory parameters

 Serum IL-6 (ng/L)

Median (IQR)

26 (19–41)

42.2 (15–52)

 − 1.196b

0.232

NS

Range

3–76

6–126

 CRP (mg/L)

Median (IQR)

16 (3.2–23)

16 (14–23)

 − 0.569b

0.569

NS

Range

0.16–116

0.73–44

 Albumin (g/dL)

Mean ± SD

3.74 ± 0.24

3.33 ± 0.47

3.337a

0.002

HS

Range

2.90–4.00

2.60–3.80

 Ferritin (ng/ml)

Median (IQR)

332 (121.6–443)

499 (345–544)

 − 2.157b

0.031

S

Range

6–1007

77.5–2000

 D dimer (mg/l)

Median (IQR)

0.65 (0.45–0.77)

0.71 (0.56–1.1)

 − 1.689b

0.091

NS

Range

0.08–1.1

0.55–2.1

 TLC (10^3/μL)

Mean ± SD

6.13 ± 2.15

7.04 ± 2.68

 − 1.036a

0.308

NS

Range

3–12.3

4.2–10.5

 Lymphocytes (10^3/μL)

Mean ± SD

1.40 ± 0.58

1.12 ± 0.36

1.425a

0.164

NS

Range

0.9–2.8

0.6–2

  1. P value > 0.05 non-significant (NS); P value < 0.05 significant (S); P value < 0.01 highly significant (HS), TLC Total leucocytic count, CRP C-reactive protein
  2. aIndependent t-test
  3. bMann Whitney test