Incidence of thrombophilic gene polymorphism (MTHFR C677T) in Egyptian COVID-19 patients and its clinical implications

The Egyptian Journal of Bronchology

Table 7 Outcome data in the study group according to MTHFR gene mutation

[n (%)]		MTHFR gene mutation		Test value	P-value	Sig
		Absent	Present
		No. = 23	No. = 10
Outcome [n (%)]
Cured/discharged	No	0 (0.0%)	3 (100.0%)	5.000^a	0.025	S
Cured/discharged	Yes	2 (100.0%)	0 (0.0%)	5.000^a	0.025	S
Continued hospitalization	No	2 (100.0%)	2 (66.7%)	0.833^a	0.361	NS
Continued hospitalization	Yes	0 (0.0%)	1 (33.3%)	0.833^a	0.361	NS
Death	No	23 (100.0%)	8 (80.0%)	4.897^a	0.027	S
Death	Yes	0 (0.0%)	2 (20.0%)	4.897^a	0.027	S
Radiological evidence of thrombosis	No	23 (100.0%)	7 (70.0%)	7.590^a	0.022	S
	PE	0 (0.0%)	2 (20.0%)
	DVT	0 (0.0%)	1 (10.0%)
Duration of hospital admission	Median (IQR)	15 (14–16)	21 (9–75)	0.000^b	1.000	NS
Duration of hospital admission	Range	14–16	6–120	0.000^b	1.000	NS

P value > 0.05 non-significant (NS); P value < 0.05 significant (S); P value < 0.01 highly significant (HS)
^aChi-square test
^bMann–Whitney test