Skip to main content
The Egyptian Journal of Bronchology
Download PDF

Effect of airway vibratory mucus disintegration on clinical morbidity and management of chronic obstructive pulmonary disease patients

Egyptian Journal of Bronchology volume 7, pages 43–49 (2013)Cite this article

Abstract

Background

Chronic obstructive pulmonary disease (COPD) is the fifth cause of morbidity and mortality in the developed world and represents a substantial economic and social burden. Patients experience a progressive deterioration characterized by airflow limitation, limited and declining performance status with chronic respiratory failure, and severe systemic manifestations/complications.

Aim of study

The aim of the study was to evaluate the effect of airway vibratory mucus disintegration on clinical morbidity and management of COPD patients.

Patients and methods

This prospective study was conducted on 30 COPD patients admitted to the Chest Department, Main University Hospital in Alexandria during the period from January 2012 to November 2012. The patients were subdivided into two groups: group I included 15 patients with COPD subjected to conventional treatment and group II included 15 patients with COPD subjected to conventional treatment and mucus disintegration by mechanical vibration.

Results

A general improvement in cough and dyspnea was observed in the two groups after treatment. Six-minute walking distance was improved after treatment in both groups, but the improvement was statistically significant only in group II after treatment. Partial pressure of oxygen in the blood (PaO2), partial pressure of CO2 in the blood (PaCO2), and bicarbonate (HCO3) and oxygen saturation (SaO2) showed significant differences before and after treatment among group II patients. The total duration of hospital stay was significantly lower in group II patients than in group I patients.

Conclusion

We can conclude that there were no adverse effects. Flutter is simple to use, inexpensive, and fully portable, and once the patient and family are instructed its use, it does not require the assistance of a caregiver. Egypt J Broncho 2013 7:43–49

References

  1. Viegi G, Pistelli F, Sherrill DL, Maio S, Baldacci S and Carrozzi L. Definition, epidemiology and natural history of COPD. Eur Respir J 2007; 30:993–1013.

    CAS  Article  Google Scholar 

  2. Rabe KF, Hurd S, Anzueto A. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007; 176:532–555.

    Article  Google Scholar 

  3. Kimathianoki M, Mitrouska L and Georgopoulas D. Management of end –stage COPD. Eur Respir Mon 2006; 38:430–450.

    Google Scholar 

  4. Halbert RJ, Natoli JL, Gano A, Badamgarav E, Buist AS, Mannino DM. Global burden of COPD: Systematic review and meta-analysis. Eur Respir J 2006; 28:523–532.

    CAS  Article  Google Scholar 

  5. Boutin Forzano S, Morean D, Kaloboka S, Gay E, Bonnefoy X, Garrozzi L, et al. Reported prevalence and co-morbidity of asthma, chronic bronchitis and emphysema: A pan-European estimation. Int J Tuberc Lung Dis 2007; 11:695–702.

    CAS  Google Scholar 

  6. AM, Perez-Padilla R, Jardim JR. Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): A prevalence study. Lancet 2005; 366:1875–1881.

    Article  Google Scholar 

  7. Lindberg A, Eriksson B, Larsson LG, Eva R, Sandstrom T and Lundback B. Seven-year cumulative incidence of COPD in an age-stratified general population sample. Chest 2006; 129:879–885.

    Article  Google Scholar 

  8. Johannessen A, Omenaas E, Bakke P, Gulsvik A. Incidence of GOLD-defined chronic obstructive pulmonary disease in a general adult population. Int J Tuberc Lung Dis 2005; 9:926–932.

    CAS  Google Scholar 

  9. Zielins J, Bednarek M, Gorecka D, Viegi G, Hurd S, CKW, et al. Increasing COPD awareness. Eur Respir J 2006; 27:833–852.

    Article  Google Scholar 

  10. Bates DV. Chronic bronchitis and emphysema. In: Macklem PT, Permutt S, (editors). The lung in the transition between health and disease. New York: Marcel Dekker Inc; 1979. 12:1–13.

    Google Scholar 

  11. Fletcher C, Peto R. The natural history of chronic airflow obstruction. BMJ 1977; 1:1645–1648.

    CAS  Article  Google Scholar 

  12. Konstan MW, Stern RC, Doershuk CF. Efficacy of the FLUTTER® device for airway mucus clearance in patients with cystic fibrosis. J Pediatr 1994; 124:689–693.

    CAS  Article  Google Scholar 

  13. Izadi F, Hajbaghery M. Effects of pursed lips breathing on ventilation and activities of daily living in patient with COPD. Webmed Cent Rehab 2011; 2:1904–1915.

    Google Scholar 

  14. Kim DS, Kim YS, Chang JH. Prevalence of COPD in Korea: A population based spirometry survey. Am J Respir Crit Care Med 2005; 1729:842–847.

    Article  Google Scholar 

  15. Stang P. The prevalence of COPD: Using smoking rates to estimate disease frequency in the general population. Chest 2000; 117:2–15.

    Article  Google Scholar 

  16. Tazanakis N, Anagnostopoulou U, Filaditaki V. Prevalence of COPD in Greece. Chest 2004; 125:892–900.

    Article  Google Scholar 

  17. Gunen H, Haceivliyagil S, Yetkin O. Prevelence of COPD: First epidemiological study of a large region in turkey. Eur J Intern Med 2008; 19:499–504.

    Article  Google Scholar 

  18. Inversen L, Hannaford PC, Price DB. Is living in a rural area good for your respiratory health? Chest 2005; 128:2059–2067.

    Article  Google Scholar 

  19. Sundblad BM, Larsson K, Nathell L. High rate of smoking abstinence in COPD patients smoking cessation by hospitalization. Nicotine Tob Res 2008; 10:883–890.

    Article  Google Scholar 

  20. Hansen J. Arterial blood gases. Clin Chest Med 1999; 10:227–237.

    Google Scholar 

  21. Calverley P. Long acting bronchodilators in COPD: How many drugs do we need? ER J 2005; 26:190–191.

    CAS  Google Scholar 

  22. Lotters F, Vantol B, Kwakkel G. Effect of controlled inspiratory muscle training in patients with COPD: A meta analysis. Eur Respir J 2002; 20:570–577.

    CAS  Article  Google Scholar 

  23. Backerman M, Magadel R, Weiner M. The effects of specific inspiratory muscle training in patient with COPD. Chest 2005; 128:3177–3182.

    Article  Google Scholar 

  24. Hem Y, Cicek H, Akbayrak Y. The effects of breathing exercises on pulmonary function tests and arterial blood gas for the patients with the COPD. Gulhane Med J 2004; 46:1–9.

    Google Scholar 

  25. Jones PW, Harding G, Wiklund L. Tests of the responsiveness of the COPD assessment test following acute exacerbation and pulmonary rehabilitation. Chest 2012; 142:134–140.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Chest Department, Faculty of Medicine, Alexandria University, Alexandria city, Egypt

    Ahmed Y. Gad MD

  2. Chest Department, Damanhour National Medical Institute, Behira city, Egypt

    Sayed A. El-Shafe

Authors
  1. Ahmed Y. Gad MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sayed A. El-Shafe
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ahmed Y. Gad MD.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Reprints and Permissions

About this article

Cite this article

Gad, A.Y., El-Shafe, S.A. Effect of airway vibratory mucus disintegration on clinical morbidity and management of chronic obstructive pulmonary disease patients. Egypt J Bronchol 7, 43–49 (2013). https://doi.org/10.4103/1687-8426.123985

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.4103/1687-8426.123985

Keyword

  • COPD
  • mucous vibration
  • airflow limitation
  • rehabilitation
  • smoking cessation