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A study of the outcome of confirmed avian flu and swine flu cases admitted to Abbassia Chest Hospital between 2006 and 2010

Egyptian Journal of Bronchology volume 8, pages 70–78 (2014)Cite this article

Abstract

Background

Type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease: H1N1, which caused swine flu in 2009, and H5N1, which caused avian flu in 2004.

Aim

The aim of this study was to evaluate the clinical and epidemiological features and the treatment outcome of confirmed cases of avian flu and swine flu admitted in Abbassia Chest Hospital between 2006 and 2010.

Patients and methods

This was a retrospective study that included 213 patients PCR-positive for influenza A H1N1 and 23 patients PCR-positive for influenza A H5N1, who were admitted to Abbassia Chest Hospital during the period from March 2006 to December 2010. The following data were collected by retrospective reviews of hospital records for each patient: epidemiological data through interview with the patient or their relatives, full history data, complete clinical examination data, full laboratory investigations, chest radiograph film at the time of admission and during the hospitalization period, a nasopharyngeal swab, ECG, and arterial blood gases. Statistical analysis of the data was then carried out.

Results

Regarding swine flu cases, there was no statistical difference with regard to the age distribution, the sex distribution, the presence of comorbidities, and the time of presentation among the studied patients. The results showed that 170 patients recovered, whereas 43 died, with a mortality rate of 20.2%. Among the avian flu cases, seven patients recovered, whereas 16 died, with a mortality rate of 69.5%. The mortality rate was high in renal patients, patients having bilateral complicating pneumonia, and in the patients who needed mechanical ventilation.

Conclusion

Some comorbidities, such as diabetes mellitus, cardiac illness, and chronic chest illness, have no implication on mortality. In contrast, renal conditions and the need of mechanical ventilation were associated with a high mortality rate. Egypt J Broncho 2014 8:70–78

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Authors and Affiliations

  1. Pulmonary Medicine Department, Faculty of Medicine, Ain Shams University, Egypt, b Abbassia Chest Hospital, 28 Othman Ebnaffan Street Heliopolis, Cairo, Egypt

    Adel Mahmoud Khattab, Khaled Mohamed Wagih & Amr Mohamed Awad Tag Eldin

Authors
  1. Adel Mahmoud Khattab
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  2. Khaled Mohamed Wagih
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  3. Amr Mohamed Awad Tag Eldin
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Correspondence to Khaled Mohamed Wagih.

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Khattab, A.M., Wagih, K.M. & Tag Eldin, A.M.A. A study of the outcome of confirmed avian flu and swine flu cases admitted to Abbassia Chest Hospital between 2006 and 2010. Egypt J Bronchol 8, 70–78 (2014). https://doi.org/10.4103/1687-8426.145689

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