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The Egyptian Journal of Bronchology
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  • Airways in health and disease
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Prevalence and predictors of chronic obstructive pulmonary disease among high-risk Egyptians

Egyptian Journal of Bronchology volume 9, pages 27–33 (2015)Cite this article

Abstract

Background

Chronic obstructive pulmonary disease (COPD) is the fourth most common cause of death in the world. COPD prevalence, morbidity, and mortality vary across countries and across different groups within countries. In Egypt, COPD is a rising significant health problem; however, information on its prevalence, morbidity, and mortality is still lacking.

Aim of the study

The first aim was to detect the prevalence of COPD among high-risk Egyptians Global using Initiative for Chronic Obstructive Lung Disease (GOLD) and FEV1/FVC < lower limit of normal (LLN) definitions. The second goal was to identify the factors predictive for diagnosis of COPD.

Patients and methods

This study included 363 randomly selected individuals with a high risk for COPD; 176 were smokers (group I), 107 were construction and brick manufacturer workers (group II), and 80 were women exposed to biomass fuel (group III). All individuals filled out a respiratory questionnaire, were clinically examined, and subjected to spirometric evaluation.

Results

The prevalence of COPD among high-risk individuals was 9.6 and 17.4% on the basis of GOLD and LLN, respectively. The sensitivity and specificity of prebronchodilator values of FEV1/FVC < LLN were 94.3 and 90.8%, respectively, for the diagnosis of COPD. However, our findings support that the postbronchodilator LLN definition is superior in ruling out the presence of COPD, as it has a good negative test specificity of 99.7%. Chest wheezes were the only symptom that was an independent predictor of COPD (odds ratio 4.80, 95% confidence interval 1.57–14.74, P = 0.02). Increasing age, smoking, and mean pack-years were also factors predictive for COPD.

Conclusion

The prevalence of COPD among high-risk individuals in Egypt was estimated to be about 10% as per GOLD. Prebronchodilator LLN is a reliable method for the diagnosis of COPD and it yields comparable results to the GOLD criteria. The main predictors for COPD diagnosis are old age, smoking history, and presence of chest wheezes.

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Author information

Authors and Affiliations

  1. Department of Chest Diseases, Faculty of Medicine, Minia University, Minia, 61111, Egypt

    Azza F. Said MD & Mohamed E. Magdy

  2. Department of Public Health and Occupational Medicine, Minia University, Egypt

    Ashraf A. Ewis

  3. Department of Clinical Pathology, Faculty of Medicine, Minia University, Egypt

    Ahmad A. Omran

  4. Mallawy Chest Hospital, Ministry of Health, Minia City, Egypt

    Micheal F. Saleeb

Authors
  1. Azza F. Said MD
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  2. Ashraf A. Ewis
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  3. Ahmad A. Omran
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  4. Mohamed E. Magdy
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  5. Micheal F. Saleeb
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Correspondence to Azza F. Said MD.

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Said, A.F., Ewis, A.A., Omran, A.A. et al. Prevalence and predictors of chronic obstructive pulmonary disease among high-risk Egyptians. Egypt J Bronchol 9, 27–33 (2015). https://doi.org/10.4103/1687-8426.153586

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  • DOI: https://doi.org/10.4103/1687-8426.153586

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