Skip to main content
Download PDF

Effect of truncal obesity on airway resistance

Egyptian Journal of Bronchology volume 9, pages 133–139 (2015)Cite this article

Abstract

Background and objective

Truncal obesity can influence respiratory mechanisms regardless of BMI. This study evaluated the impact of truncal obesity on both spirometry and impulse oscillometry (IOS).

Patients and methods

The study included 102 patients recruited from the Outpatient Department of Ain Shams University Hospital. All patients were subjected to clinical examination, anthropometric measurements, IOS, and spirometry. According to BMI, the patients were categorized into the obese group (71 patients) and the nonobese group (31 patients). The obese group was subclassified into overweight, obese, and morbidly obese groups. The obese subgroup was reclassified according to waist to hip ratio (WHR) into the truncal obese group (41 patients) and the nontruncal obese group (30 patients). The data collected were comparatively analyzed using either the independent-samples t-test or one-way analysis of variance. Pearson’s correlation coefficient was used to study the correlations between data. Multiple linear regression analysis was carried out to examine the simultaneous influences of anthropometric measures on the IOS data.

Results

There were significant differences in IOS and spirometry data between the obese and nonobese groups as well as among the four groups. Regarding WHR, there were significant correlations with IOS data and negative correlations with spirometry data except maximal mid expiratory flow. Using multiple linear regression analysis, it was revealed that WHR was the most powerful predictor for R5. BMI followed by WHR was the most powerful predictor for R5–R20.

Conclusion

Truncal obesity significantly affects airway resistance, as evaluated by spirometry and IOS.

References

  1. Chen Y, Rennie D, Cormier YF, Dosman J. Waist circumference is associated with pulmonary function in normal-weight, overweight, and obese subjects. Am J Clin Nutr 2007; 85:35–39.

    Article  CAS  Google Scholar 

  2. Salome CM, King GG, Berend N. Physiology of obesity and effects on lung function. J Appl Physiol 2010; 108:206–211.

    Article  Google Scholar 

  3. Ochs-Balcom HM, Grant BJ, Muti P, Sempos CT, Freudenheim JL, Trevisan M, et al. Pulmonary function and abdominal adiposity in the general population. Chest 2006; 129:853–862.

    Article  Google Scholar 

  4. Jubber AS. Respiratory complications of obesity. Int J Clin Pract 2004; 58:573–580.

    Article  CAS  Google Scholar 

  5. Chen Y, Rennie D, Cormier Y, Dosman JA. Waist circumference associated with pulmonary function in children. Pediatr Pulmonol 2009; 44:216–221.

    Article  Google Scholar 

  6. Klein, S, Allison, DB, Heymsfield, SB, Kelley, DE, Leibel, RL, Nonas, C, Kahn, R. Waist circumference and cardiometabolic risk: a consensus statement from shaping America’s health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association. Obesity 2007; 15:1061–1067.

    Article  Google Scholar 

  7. Wehrmeister F, Menezes A, Muniz L, Martínez-Mesa J, Domingues R, Horta B. Waist circumference and pulmonary function: a systematic review and meta-analysis. Syst Rev 2012; 1:55.

    Article  Google Scholar 

  8. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al. Standardisation of spirometry. Eur Respir J 2005; 26:319–338.

    Article  CAS  Google Scholar 

  9. Oostveen E, MacLeod D, Lorino H. The forced oscillation technique in clinical practice. Methodology, recommendations and future developments. ERS Task Force. Eur Respir J 2003; 22:1026–1041.

    Article  CAS  Google Scholar 

  10. Al-Mutairi S, Sharma P, Al-Alawi A, Al-Deen J. Impulse oscillometry: an alternative modality to the conventional pulmonary function test to categories obstructive pulmonary disorders. Clin Exp Med 2007; 7:56–64.

    Article  CAS  Google Scholar 

  11. El-Naggar T, Mansour M, Mounir N, Mukhtar M. The role of impulse oscillometry in assessment of airway obstruction in smokers and ex-smokers. Egypt J Chest Dis Tubercul 2012; 61:323–328.

    Article  Google Scholar 

  12. Yap JC, Watson RA, Gilbey S, Pride NB. Effects of posture on respiratory mechanics in obesity. J Appl Physiol 1995; 79:1199–1205.

    Article  CAS  Google Scholar 

  13. Robinson PD. Obesity and its impact on the respiratory system. Paediatr Respir Rev 2014; 15:219–226.

    PubMed  Google Scholar 

  14. Anderson WJ, Lipworth BJ. Relationships between impulse oscillometry, spirometry and dyspnoea in COPD. J R Coll Physicians Edinb 2012; 42:111–115.

    Article  CAS  Google Scholar 

  15. Casey L, Moran E, Gunn J. Impulse oscillometry (IOS) provides important additional information during methacholine challenge. Chest 2011; 140:974A.

    Article  Google Scholar 

  16. Zerah F, Harf A, Perlemuter L, Lorino H, Lorino AM, Atlan G. Effects of obesity on respiratory resistance. Chest 1993; 103:1470–1476.

    Article  CAS  Google Scholar 

  17. Parameswaran K, Todd DC, Soth M. Altered respiratory physiology in obesity. Can Respir J 2006; 13:202–210.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculty of Medicine, Ain Shams University, Cairo, Egypt

    Hesham A. AbdelHalim MD & Ahmed M. ElMansoury

  2. Faculty of Medicine, Department of Pulmonary Medicine, October 6 University, 6th of October City, Egypt

    Heba H. AboElNaga

Authors
  1. Hesham A. AbdelHalim MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Heba H. AboElNaga
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ahmed M. ElMansoury
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hesham A. AbdelHalim MD.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

AbdelHalim, H.A., AboElNaga, H.H. & ElMansoury, A.M. Effect of truncal obesity on airway resistance. Egypt J Bronchol 9, 133–139 (2015). https://doi.org/10.4103/1687-8426.158043

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.4103/1687-8426.158043

Keywords