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Effect of continuous positive airway pressure on oxidative stress accompanied by obstructive sleep apnea
Egyptian Journal of Bronchology volume 9, pages 192–197 (2015)
Abstract
Introduction
In obstructive sleep apnea (OSA), there is increased oxidative stress.
Aim of this work
This study aimed to examine the effect of continuous positive airway pressure (CPAP) on oxidative stress occurring in OSA.
Participants and methods
The present study was carried out on 40 individuals classified into four groups: group I included 10 control participants, group II included 10 obese individuals without OSA, group III included 10 patients with mild to moderate OSA, and group IV included 10 patients with severe OSA. Sleep study was carried out, and Thiobarbituric acid-reactive substance and superoxide dismutase enzyme were measured.
Results
Thiobarbituric acid-reactive substance was significantly increased, but superoxide dismutase was significantly decreased in group IV, and CPAP led to an improvement in this condition.
Conclusion
OSA leads to increased oxidative stress that improved with the use of CPAP.
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El-Kholy, M.G., El-Shafey, B.I., Hantera, M.S. et al. Effect of continuous positive airway pressure on oxidative stress accompanied by obstructive sleep apnea. Egypt J Bronchol 9, 192–197 (2015). https://doi.org/10.4103/1687-8426.158092
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DOI: https://doi.org/10.4103/1687-8426.158092