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Sleep-disordered breathing in ischemic cardiomyopathy and hypertensive heart failure patients



The aims of this study are to (a) detect the effect of different types of heart diseases [ischemic, cardiomyopathy, hypertensive heart failure (HF)] on the association with sleep disorders, and to (b) identify the relationship between Cheyne–Stokes respiration (CSR) and left ventricular dysfunction.

Materials and methods

In a cross-sectional study involving 100 HF patients, we performed echocardiography and a fullnight attended polysomnography for all patients.


In all, 47.9% of patients with ischemic heart disease had obstructive sleep apnea (OSA), whereas 37.5% had central sleep apnea (CSA). OSA was highly prevalent in patients with hypertensive heart disease (79.2%). On the other hand, 50.0% patients with dilated cardiomyopathy (DCM) had CSA, whereas 39.3% had OSA. Patients with DCM had a significant increase in the central apnea index (11.05±9.19 events/h), as well cycle length of CSR (68.14 ±13.26 s), as compared with other groups. There was an inverse increase of cycle length with reduction in left ventricular ejection fraction (LVEF) (LVEF≥50% had a cycle length of 41.55±10.84 s, whereas those with LVEF≤30% had a longer mean cycle length of 69.23±18.09 s).


Sleep-disordered breathing is a common disorder in different groups of HF. OSA was prevalent in ischemic and hypertensive heart disease, whereas CSA was prevalent in DCM. There was a significant increase in cycle length of CSR with a reduction in LVEF.


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Correspondence to Doaa Magdy MD.

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Salama, S., Omar, A., Ahmed, Y. et al. Sleep-disordered breathing in ischemic cardiomyopathy and hypertensive heart failure patients. Egypt J Bronchol 11, 154–160 (2017).

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  • cheyne–stokes respiration
  • heart failure
  • sleep-disordered breathing