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The Egyptian Journal of Bronchology
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Primary pulmonary extraskeletal Ewing sarcoma/Primitive neuroectodermal tumor: Two case reports

Egyptian Journal of Bronchology volume 11, pages 161–164 (2017)Cite this article

Abstract

Primary pulmonary extraskeletal Ewing sarcoma (EES)/ primitive neuroectodermal tumor is an extremely rare tumor with only few cases reported in the literature. In this study, we present two cases of primary pulmonary EES diagnosed and treated at our institution. The median age was 20 years (range: 19–21). Cough, dyspnea, and hemoptysis were the predominant features at presentation, associated with a large lung mass on imaging. Image-guided core needle biopsies were the diagnostic modalities for both patients. Initial histopathology showed malignant small round cell tumor, which has been confirmed by immunohistochemistry as EES. Both patients received neoadjuvant chemotherapy followed by surgery; postoperative pathology for the first patient showed 98% tumor necrosis, whereas the second patient’s pathology showed no evidence of residual tumor after complete surgical excision.

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Authors and Affiliations

  1. Department of Chest, Faculty of Medicine, Al-Zahraa University Hospital, Cairo, Al-Abbassia, 11517, Egypt

    Eman Sobh MD

  2. Department of Clinical Oncology, Al Hussein University Hospital, Faculty of Medicine, Al-Azhar University, Egypt

    Wael H. El-Sheshtawy

  3. Department of Pathology, Cairo University, Cairo, Egypt

    Shady E. Anis

Authors
  1. Eman Sobh MD
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  2. Wael H. El-Sheshtawy
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  3. Shady E. Anis
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Correspondence to Eman Sobh MD.

Additional information

This study was previously presented as oral abstract in Al-Azhar Grand Round and Alexandria Pediatric Pulmonology Conference.

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Sobh, E., El-Sheshtawy, W.H. & Anis, S.E. Primary pulmonary extraskeletal Ewing sarcoma/Primitive neuroectodermal tumor: Two case reports. Egypt J Bronchol 11, 161–164 (2017). https://doi.org/10.4103/ejb.ejb_48_16

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  • DOI: https://doi.org/10.4103/ejb.ejb_48_16

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