Skip to main content

Broncial stump aspergillosis, an unusual cause of hemoptysis, and review of the literature

Abstract

Aspergillus species are ubiquitous dimorphic molds found in an environment. of the 250 species, few of them are pathogenic to human and can cause various lung involvements, tracheobronchial being one of the variant. Bronchial stumps and anastomosis are prone for fungal infection and can present with cough, hemoptysis, central airway obstruction and bronchopleural fistula with its highest incidence in patients with lung transplantation. Its occurrence in other types of lung surgery is very rare and 20 cases have been described in English medical literature till date since first published in 1969. We present a case of recurrent hemoptysis caused by bronchial stump aspergillosis, first reporting from India, and systematically analyze the literature for all the reported cases of bronchial stump and anastomosis aspergillosis in patients with lung surgery other than transplantation.

References

  1. Al-Alawi A, Ryan CF, Flint JD, Muller NL. Aspergillus-related lung disease. Can Respir J 2005; 12:377–387.

    Article  Google Scholar 

  2. Krenke R, Grabczak EM. Tracheobronchial manifestations of Aspergillus infections. Scientific World J 2011; 11:2310–2329.

    Article  Google Scholar 

  3. Sawasaki H, Horie K, Yamada M, Tajima G, Katsura S, Naito Y, et al. Bronchial stump aspergillosis. Experimental and clinical study. J Thorac Cardiovasc Surg 1969; 58:198–208.

    CAS  Article  Google Scholar 

  4. Le Rochais JP, Icard P, Simon T, Poirier P, Evrard C. Bronchial stump aspergillosis. Ann Thorac Surg 2000; 70:302–304.

    Article  Google Scholar 

  5. Rissmiller R, Copley P, Conforti J. Localized bronchopulmonary aspergillosis colonizing a previous sleeve resection for carcinoid tumor resulting in critical airway obstruction. J Bronchol 2004; 11:250–253.

    Article  Google Scholar 

  6. Parry MF, Coughlin FR, Zambetti FX. Aspergillus empyema. Chest 1982; 81:768–770.

    CAS  Article  Google Scholar 

  7. Roig J, Ruiz J, Puig X, Carreres A, Morera J. Bronchial stump aspergillosis four years after lobectomy. Chest 1993; 104:295–296.

    CAS  Article  Google Scholar 

  8. Noppen M, Claes I, Maillet B, Meysman M, Monsieur I, Vincken W. Three cases of bronchial stump aspergillosis: unusual clinical presentations and beneficial effect of oral itraconazole. Eur Respir J 1995; 8:477–480.

    CAS  Article  Google Scholar 

  9. Garcia-Olive I, Andreo F, Rosinal O, Sanz-Santos J, Font A, Monso E. Bronchial stump aspergillosis after lobectomy for lung cancer as an unusual cause of false positive fluorodeoxyglucose positron emission tomography and computed tomography: a case report. J Med Case Rep 2011; 5:72.

    Article  Google Scholar 

  10. Tokuishi K, Yamashita S, Hashimoto T, Moroga T, Miyawaki M, Chujo M, et al. Bronchial stump aspergillosis after stapled lobectomy for lung cancer. Ann Thorac Surg 2012; 94:1324–1326.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dipesh Maskey MD,DM.

Additional information

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work noncommercially, as long as the author is credited and the new creations are licensed under the identical terms.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Maskey, D., Agrawal, R. Broncial stump aspergillosis, an unusual cause of hemoptysis, and review of the literature. Egypt J Bronchol 12, 129–135 (2018). https://doi.org/10.4103/ejb.ejb_9_17

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.4103/ejb.ejb_9_17

Key words

  • aspergillosis
  • bronchial anastomosis
  • bronchial stump
  • hemoptysis